2026-06-14T05:05:12Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/48262025-03-27T09:17:35Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Castro Ferreira, Eduardo de
author
Cruz, Israel
author
Cañavate, Carmen
author
de Melo, Lutiana Amaral
author
Sampaio Pereira, Agnes Antônia
author
Madeira, Filipe AM
author
Alves Nogueira Valério, Sofia
author
Morais Cunha, Heitor
author
Pereira Paglia, Adriano
author
Ferreira Gontijo, Célia Maria
funder
Fundação de Amparo à Pesquisa do Estado de São Paulo Minas Gerais (Brasil)
funder
National Council for Scientific and Technological Development (Brasil)
funder
Oswaldo Cruz Foundation
funder
EC-LeishEpiNet-SA Consortium
2017-09-04T16:30:37Z
2017-09-04T16:30:37Z
2015-03-20
BMC Vet Res. 2015; 11:71
10.1186/s12917-015-0392-y
1746-6148
BMC Veterinary Research
http://hdl.handle.net/20.500.12105/4826
BACKGROUND: In Brazil Leishmania braziliensis and L. infantum are the principal species responsible for cutaneous and visceral leishmaniases, respectively. Domestic dogs are the main reservoirs of visceral leishmaniasis, while rodents and marsupials are the main reservoirs for cutaneous leishmaniasis. It has also been suggested that dogs could play a role in transmission of cutaneous leishmaniasis. The identification of the species of Leishmania, the reservoirs, and the vectors involved in each particular transmission cycle is critical for the establishment of control activities. Belo Horizonte has emerged as an endemic region for leishmaniases, however, epidemiological studies assessing the contribution of wild reservoirs to transmission are scarce in the area. The aim of this study was to investigate Leishmania spp. infection in possible reservoirs of an urbanized area. RESULTS: A high rate of infection was found in small mammals (64.9%) and dogs (DG1 30.4% and DG2 48.6%). The presence of L. infantum and L. braziliensis was detected in small mammals and dogs, and mixed infections by both species were detected in rodents which, to the best of our knowledge, is the first description of this phenomenon in an urban area. Additionally, L. amazonensis was detected in the canine samples. CONCLUSION: The possible role of these animals as a source of infection of the vector of each species of Leishmania identified should not be overlooked and should be taken into account in future control activities. The results of mixed infection by L. braziliensis and L. infantum in cosmopolitan rodents as M. musculus and R. rattus, may have important implications in the context of the control of leishmaniasis in urban areas, especially when considering that these rodents live in close relationship with human dwellings, especially those in more precarious conditions.
eng
Leishmania
Hosts
Reservoir
Small mammals
Dogs
Mixed-infections
Mixed infection of Leishmania infantum and Leishmania braziliensis in rodents from endemic urban area of the New World
research article
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https://repisalud.isciii.es/bitstreams/9a6ba899-2b2b-483b-b51b-76d51de30ab3/download
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application/pdf
MixedInfectionOfLeishmania_2015
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text/plain
12917_2015_Article_392.pdf.txt
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https://repisalud.isciii.es/bitstreams/829603f7-561f-4618-b6eb-2117dfbf132f/download
File
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text/plain
MixedInfectionOfLeishmania_2015.txt