2026-10-04T23:20:30Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/277252026-09-22T00:16:06Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19608col_20.500.12105_19609
Repisalud
author
Hernando Sebastian, Victoria
author
Cuevas, Maria Teresa
author
Perez-Olmeda, Mayte
author
Tasias, Maria
author
Vera, Mar
author
Jaen, Angels
author
Mena, Alvaro
author
Jarrin Vera, Inmaculada
author
Diaz Franco, Asuncion
author
CoRIS-HIV Biobank
funder
Instituto de Salud Carlos III
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
2026-09-21T11:13:59Z
2026-09-21T11:13:59Z
2021-06
Victoria Hernando, Maria Teresa Cuevas, Maria Teresa Pérez-Olmeda, Maria Tasias, Mar Vera, Angels Jaen, Alvaro Mena, Inma Jarrin, Asunción Diaz & CoRIS-HIV Biobank (2021): Recent infections among newly diagnosed cases of HIV infection in Spain, 2015–2016. National estimates using cohort data, Infectious Diseases, DOI: 10.1080/23744235.2021.1893377.
10.1080/23744235.2021.1893377
Infectious Diseases
33685324
https://hdl.handle.net/20.500.12105/27725
Background: To estimate the prevalence of recent infection (RI) among people newly diagnosed with HIV in Spain using a representative sample collected by the AIDS Research Network cohort (CoRIS) during 2015-2016. Methods: Stratified sampling of CoRIS data was used with proportional allocation by mode of transmission of new HIV diagnoses notified to National Surveillance System. Samples used were from patients in the CoRIS cohort with available stored plasma collected within 6 months after diagnosis. Weighted methods were used to estimate the prevalence of RI and multivariate logistic regression models were used to determine associated factors. Results: Of the 669 individuals included, 55.1% were men who had sex with men (MSM), 24.6% were heterosexual, and 20.3% were non-MSM non-heterosexual. The weighted prevalence of RI was 11.8% (95% Confidence interval [CI] 9.4-14.8%) overall, 15.5% (12.2-19.4%) among MSM, 6.3% (3.9-10.0%) among heterosexual, and 8.6% (3.2-20.9%) in non-MSM non-heterosexual persons. Factors associated with prevalence of RI were: MSM (OR 2.05; 95% CI 1.02-4.14) vs. heterosexual, being Spanish (OR 2.92; 1.36-6.26) or European (OR 3.42; 1.28-9.13) vs. Latin American, having a secondary or higher education level (OR 3.08; 0.95-1.00) vs. primary, and having a CD4 count of 350-499 (OR 3.26; 1.46-7.30) or >500 (OR 6.26; 2.92-13.39) vs. <350 cells/mm3. Conclusions: In the absence of direct data from surveillance systems, the use of cohort data is a very valuable option for identifying the prevalence of RI at national level. This is the first nationwide study carried out in Spain to determine the prevalence of RI using an avidity assay.
eng
HIV
Cohort study
Recent infection
Surveillance
Recent infections among newly diagnosed cases of HIV infection in Spain, 2015-2016. National estimates using cohort data.
research article
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5f95fd3ffd0903dd7c9c224e630e1b26
1395089
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RecentInfectionsNewlyDiagnosed_2021.pdf