2026-10-04T23:20:29Zhttps://repisalud.isciii.es/rest/oai/request
oai:repisalud.isciii.es:20.500.12105/277162026-09-17T13:27:43Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud author Barbiero, Anna author Moreno, Javier author Bernardo, Lorena author Lozano-Rendal, Marina author Solana, Jose Carlos author Sanchez Herrero, Carmen author Marco Vinuesa, Arantxa author Cuenca, Paula author San Martín, Juan Víctor author Lagi, Filippo author Zammarchi, Lorenzo author Spinicci, Michele author Bartoloni, Alessandro author Granozzi, Bianca author Bacchiega, Michele author De Pascali, Alessandra Mistral author Balducelli, Emma author Ortalli, Margherita author Zaghi, Irene author Varani, Stefania author Carrillo, Eugenia 2026-09-15T12:18:20Z 2026-09-15T12:18:20Z 2026-09-10 Carrillo, Eugenia... [et al.]. Clinical significance of asymptomatic Leishmania infantum infection in people living with HIV [Dataset], Versión de septiembre de 2026. Repositorio Institucional de Salud REPISALUD. https://doi.org/10.4321/repisalud.27716. 10.4321/repisalud.27716 https://hdl.handle.net/20.500.12105/27716 This dataset contains demographic, clinical, immunological and molecular data from 204 people living with HIV (PLWH) recruited between 2013 and 2023 in Spain and Italy, all residing in Leishmania infantum-endemic areas. For each participant, the database includes age, sex, birthplace, cohort, CD4+ T-cell count, HIV viral load, antiretroviral treatment information, and the results of three complementary screening methods for asymptomatic Leishmania infection: kDNA real-time PCR, ELISA serology, and a whole blood stimulation assay (WBA) measuring parasite-specific cytokine responses (IFN-γ, IL-2 and IP-10). In addition, the dataset contains follow-up information for individuals with positive screening results, including repeated PCR, serological and immunological assessments and clinical monitoring for progression to visceral leishmaniasis. No cases of progression to overt VL were recorded during follow-up. eng HIV AIDS Leishmania infantum Asymptomatic infection Surveillance Visceral leishmaniasis Whole blood stimulation assay ELISA PCR Immunocompromised patients Southern Europe Clinical significance of asymptomatic Leishmania infantum infection in people living with HIV_data set dataset 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 URL https://repisalud.isciii.es/bitstreams/7edcdec0-5ade-47db-8e12-1f4d9b91e77e/download File MD5 c2e91a34e8ffe201cd44ba1e03fb0190 44500 application/vnd.openxmlformats-officedocument.spreadsheetml.sheet ClinicalSignificanceAsymptomaticLeishmania_2026.xlsx URL https://repisalud.isciii.es/bitstreams/2d44fb99-7cbe-4c65-83f3-128fd145c6d0/download File MD5 aa9813ca9fc3bfecc89c3a6e3ba21f6c 9694 text/plain readme_ClinicalSignificanceAsymptomaticLeishmania_2026.txt