2026-05-14T16:33:07Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/274452026-04-28T00:16:21Zcom_20.500.12105_19586com_20.500.12105_2202col_20.500.12105_19587
Repisalud
author
Hesse, Kerrick
author
Aung, Nay
author
Petersen, Steffen E
author
Siripanthong, Bhurint
author
Captur, Gabriella
author
Yeo, Khung Keong
author
Friedrich, Matthias G
author
Jaddoe, Vincent W V
author
Dörr, Marcus
author
Pischon, Tobias
author
Bluemke, David A
author
Ibáñez, Borja
author
Fuster, Valentin
author
Chahal, C Anwar A
author
Khanji, Mohammed Y
2026-04-27T09:44:32Z
2026-04-27T09:44:32Z
2026-02-20
JACC Cardiovasc Imaging. 2026 Feb 20:S1936-878X(26)00050-1.
JACC. Cardiovascular Imaging
41758108
https://hdl.handle.net/20.500.12105/27445
Epidemiological population studies may include cardiac magnetic resonance (CMR)-derived phenotyping and large-scale genotyping, providing unprecedented level of detail to investigate novel gene-lifestyle-disease interactions. The systematic review presents high-level summaries and critically appraises contemporary challenges and biobank opportunities. The authors identified 17 relevant biobanks by searching "CMR," "genome" and "population study" on MEDLINE, EMBASE, and Web of Science 2025. Collectively, studies recruited ∼1 million participants with stored blood samples for extensive genomic analyses, of whom >180,000 have or will undergo CMR. Use of expansive personal data must safeguard participant confidentiality, encourage technological standardization, and champion inclusivity and sustainability. Application of genotypic and imaging-derived phenotypic information will be readily translatable to clinical practice through investigation of, among others, new therapeutic targets and highly sensitive and specific biomarkers. Imaging biobanks are accessible to researchers by application. This systematic review should inspire greater use and cross-collaboration and facilitate powerful discoveries in more heterogeneous population samples.
eng
cardiovascular magnetic resonance
genomics
population study
Systematic Review of International Population Studies With Cardiac Magnetic Resonance and Genomics Research Data ("Imagenomics").
research article
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Systematic Review of International Population_JACC Cardiovasc Imaging_2026.pdf