2026-06-14T03:30:33Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/271912026-01-29T01:20:04Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19611
Repisalud
author
Gadisa, Endalamaw
author
Custodio, Estefania
author
Cañavate, Carmen
author
Sordo, Luis
author
Chicharro, Carmen
author
Abebe, Zelalem
author
Nieto Martinez, Francisco Javier
author
Chicharro, Carmen
author
Aseffa, Abraham
author
Yamuah, Lawrence
author
Engers, Howard
author
Moreno, Javier
author
Cruz, Israel
2026-01-28T18:09:02Z
2026-01-28T18:09:02Z
2012-05
Gadisa E, Custodio E, Cañavate C, Sordo L, Abebe Z, Nieto J, Chicharro C, Aseffa A, Yamuah L, Engers H, Moreno J, Cruz I. Usefulness of the rK39-immunochromatographic test, direct agglutination test, and leishmanin skin test for detecting asymptomatic Leishmania infection in children in a new visceral leishmaniasis focus in Amhara State, Ethiopia. Am J Trop Med Hyg. 2012 May;86(5):792-8. doi: 10.4269/ajtmh.2012.11-0196. PMID: 22556076; PMCID: PMC3335682.
10.4269/ajtmh.2012.11-0196
The American Journal of Tropical Medicine and Hygiene
22556076
https://hdl.handle.net/20.500.12105/27191
In areas where visceral leishmaniasis is anthroponotic, asymptomatically infected patients may play a role in transmission. Additionally, the number of asymptomatic patients in a disease-endemic area will also provide information on transmission dynamics. Libo Kemkem and Fogera districts (Amhara State, Ethiopia) are now considered newly established areas to which visceral leishmaniasis is endemic. In selected villages in these districts, we conducted a study to assess the usefulness of different approaches to estimate the asymptomatic infection rate. Of 605 participants, the rK39 immunochromatographic test was able to detect asymptomatic infection in 1.5% (9 of 605), direct agglutination test in 5.3% (32 of 605), and leishmanin skin test in 5.6% (33 of 589); the combined use of serologic methods and leishmanin skin test enabled detecting asymptomatic infection in 10.1% (61 of 605). We conclude that the best option to detect asymptomatic infection in this new visceral leishmaniasis-endemic focus is the combined use of the direct agglutination test and the leishmanin skin test.
eng
Usefulness of the rK39-immunochromatographic test, direct agglutination test, and leishmanin skin test for detecting asymptomatic Leishmania infection in children in a new visceral leishmaniasis focus in Amhara State, Ethiopia.
research article
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URL
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Usefulness_rK39-immunochromatographicTest_2012.pdf
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https://repisalud.isciii.es/bitstreams/f21942d6-f4fc-4f19-b670-fe649c5c8e15/download
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Figures_Usefulness_rK39-immunochromatographicTest_2012.ppt