2026-07-21T08:08:43Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/270792025-12-18T12:57:50Zcom_20.500.12105_19586com_20.500.12105_2202col_20.500.12105_19587
Repisalud
author
Keramida, Kalliopi
author
Lopez-Fernandez, Teresa
author
Anker, Markus S
author
Petrie, Mark C
author
Ameri, Pietro
author
Anderson, Lisa J
author
Bergler-Klein, Jutta
author
Deswal, Anita
author
Farmakis, Dimitrios
author
Ibañez, Borja
author
Lam, Carolyn S P
author
Lang, Ninian N
author
Lyon, Alexander R
author
Mirabel, Mariana
author
Moura, Brenda
author
Paulus, Walter J
author
Rakisheva, Amina
author
Savarese, Gianluigi
author
Senni, Michele
author
Tocchetti, Carlo Gabriele
author
Metra, Marco
author
Filippatos, Gerasimos
2025-12-17T15:03:08Z
2025-12-17T15:03:08Z
2025-09-12
Eur J Heart Fail . 2025 Sep 12.
EUROPEAN JOURNAL OF HEART FAILURE
40938778
https://hdl.handle.net/20.500.12105/27079
Heart failure with preserved ejection fraction (HFpEF) is increasingly recognized in cancer patients and survivors, yet it remains underdiagnosed and its epidemiology largely unknown. This statement underscores the imperative need to include HFpEF in the cardiotoxicities identified during or after anticancer treatments. It also highlights the prognostic value of pre-existing HFpEF for periprocedural and cardiotoxicity risk and it discusses the challenges in the diagnosis and treatment of HFpEF in cancer patients. It also explores the aetiologic role of anticancer therapies (chemotherapy, targeted and hormonal therapies and radiotherapy) in the pathogenesis of HFpEF. Special emphasis is given on the importance of considering HFpEF from cancer diagnosis throughout treatment and survivorship and provides useful insights for cardiologists and oncologists in the monitoring and management of these patients. Finally, it highlights the key gaps in current knowledge that require further investigation through well-designed research trials to enhance our understanding and improve clinical outcomes.
eng
Cancer
Cardiotoxicity
Chemotherapy
Heart failure with preserved ejection fraction
Radiotherapy
Heart failure with preserved ejection fraction in cancer patients and survivors. A scientific statement of the Heart Failure Association of the ESC and the ESC Council of Cardio-Oncology.
research article
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Heart failure with preserved ejection fraction_Eur J Heart Fail_2025.pdf