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00925njm 22002777a 4500 dc Instituto de Salud Carlos III. Subdirección General de Evaluación y Fomento de la Investigación author 2025-11 The Alliance of Health Research Institutes provides a stable framework for collaboration and joint work between the Institute of Health Carlos III (hereinafter ISCIII) and the Health Research Institutes accredited by the Spanish Ministry of Science, Innovation and Universities (hereinafter IIS). Established by the ISCIII in November 2019, the Alliance has, over these five years, consolidated itself as a forum for reflection, shared learning and cooperative innovation in biomedical R&D&I, with a particular focus on the Spanish National Health System. As such, it forms part of the Spanish System of Science, Technology and Innovation (SECTI). In line with the growing recognition of the role of public research in driving European innovation, as highlighted by the European Patent Office (EPO) in its recent report Public Research and Innovation in Europe (2025), the accredited IIS constitute an essential pillar in the generation of knowledge and the creation of value in health through technological innovation. This document, The Technology Portfolio of Spanish Accredited Health Research Institutes, is an exercise in transparency aligned with Open Science policies, and is structured around three specific objectives: 1.To identify and systematise the portfolio of technologies developed within the IIS environment, highlighting their contribution to the generation of research results with potential for transfer and practical application. 2.To characterise and classify these technologies according to their scientific and technological nature, grouping them into five main categories. To facilitate consultation, the document organises the technologies into the following categories: A:.Pharmaceuticals and Biotechnology. B: Medical Devices. C:Diagnostics and Imaging. D:Digital health and IT. E:.Others. 3.To promote their valorisation and transfer, fostering connections between the IIS, the industrial sector and other stakeholders, with the aim of transforming research results into products, services and solutions that have a real impact on improving citizens’ health. Overall, this portfolio is conceived as a tool to highlight the role of the IIS within the European research and innovation system, contributing to the valorisation of scientific results, the promotion of public-private collaboration, and the transformation of knowledge into solutions that improve people’s lives. 156250391 https://hdl.handle.net/20.500.12105/26962 Health Research Institutes Innovation Biomedical Tecnology Patent Valorisation Transfer Portfolio of technologies Pharmaceuticals Biotechnology Medical Devices Diagnostics and Imaging Digital Health The Technology Portfolio of Spanish Accredited Health Research Institutes