2026-05-20T04:01:55Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/269522025-12-18T13:02:10Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_16959
Repisalud
author
Contreras-Llanes, Manuel
author
Alguacil, Juan
author
Capelo, Rocío
author
Gómez-Ariza, José Luis
author
García-Pérez, Javier
author
Perez-Gomez, Beatriz
author
Martin-Olmedo, Piedad
author
Santos-Sánchez, Vanessa
funder
Junta de Andalucía
funder
Universidad de Huelva
funder
Instituto de Salud Carlos III
funder
Consejería de Salud y Consumo de la Junta de Andalucía
2025-11-03T11:18:05Z
2025-11-03T11:18:05Z
2025-02-08
Contreras-Llanes M, Alguacil J, Capelo R, Gomez-Ariza JL, Garcia-Perez J, Perez-Gomez B, Martin-Olmedo P, Santos-Sanchez V. Internal cumulated dose of toxic metal(loid)s in a population residing near a Naturally Occuring Radioactive Material waste stacks and an industrial heavily polluted area with high mortality rates in Spain. J Xenobiot 2025, 15(1), 29. https://doi.org/10.3390/jox15010029.
10.3390/jox15010029
Journal of Xenobiotics
39997372
https://hdl.handle.net/20.500.12105/26952
Huelva is a city in SW Spain with 150,000 inhabitants, located in the proximity of two heavy chemical industry complexes, the highest naturally occurring radioactive material (NORM) waste (phosphogypsum) stacks of Europe and a highly polluted estuary, with elevated cardiovascular disease and cancer mortality rates. This study analyses the association between cumulated exposure levels to 16 metal(loid)s (Al, As, Cd, Co, Cr, Cu, Fe, Mn, Mo, Ni, Pb, Se, Tl, U, V, and Zn) measured in the toenail of a sample ( = 55 participants) of the general control population of Huelva City who were involved in the MCC-Spain study and the spatial proximity patterns to the local polluting sources. Residents of the city of Huelva have higher levels of Fe, Ni, Cr, Se, As, and Co in their toenails compared to the levels found in populations with similar characteristics living in non-polluted areas. Moreover, the highest concentrations of As, Pb, Cd, Mo, and Se were found in toenails of participants living near the NORM waste stack, while the highest Cu, Zn, and Al contents corresponded to people residing near the industrial area. The spatial distribution of most of the metal(loid)s studied appears to be mainly controlled by anthropogenic factors.
eng
Huelva
Industrial polluted area
kriging
Metal(loid)s
Naturally occurring radioactive material
Phosphogypsum
Principal component analysis
Spatial distribution
Toenails
Internal Cumulated Dose of Toxic Metal(loid)s in a Population Residing near Naturally Occurring Radioactive Material Waste Stacks and an Industrial Heavily Polluted Area with High Mortality Rates in Spain.
research article
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0fdb7b334e41026747149d05fb203324
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InternalCumulatedDoseToxic_2025.pdf