2026-04-29T16:56:06Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/267532025-12-18T13:01:20Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605

00925njm 22002777a 4500 dc Rueda-Alaña, Eneritz author Senovilla-Ganzo, Rodrigo author Grillo, Marco author Vázquez, Enrique author Marco-Salas, Sergio author Gallego-Flores, Tatiana author Ordeñana-Manso, Aitor author Ftara, Artemis author Escobar, Laura author Benguría, Alberto author Quintas, Ana author Dopazo, Ana author Rábano, Miriam author Vivanco, María dM author Aransay, Ana María author Garrigos, Daniel author Toval, Ángel author Ferrán, José Luis author Nilsson, Mats author Encinas-Pérez, Juan Manuel author De Pittà, Maurizio author García-Moreno, Fernando author 2025-01-02 The amniote pallium contains sensory circuits that are structurally and functionally equivalent, yet their evolutionary relationship remains unresolved. We used birthdating analysis, single-cell RNA and spatial transcriptomics, and mathematical modeling to compare the development and evolution of known pallial circuits across birds (chick), lizards (gecko), and mammals (mouse). We reveal that neurons within these circuits' stations are generated at varying developmental times and brain regions across species and found an early developmental divergence in the transcriptomic progression of glutamatergic neurons. Our research highlights developmental distinctions and functional similarities in the sensory circuit between birds and mammals, suggesting the convergence of high-order sensory processing across amniote lineages. Science . 2025 Jan 2;387(6735):eadp3411. Science 39946453 https://hdl.handle.net/20.500.12105/26753 Evolutionary convergence of sensory circuits in the pallium of amniotes.