2026-05-16T21:49:04Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/265732025-12-18T12:59:34Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Magallanes, Sergio
author
Llorente, Francisco
author
Ruiz-López, María José
author
Martínez-de la Puente, Josué
author
Ferraguti, Martina
author
Gutiérrez-López, Rafael
author
Soriguer, Ramón
author
Aguilera-Sepúlveda, Pilar
author
Fernández-Delgado, Raúl
author
Jiménez-Clavero, Miguel Ángel
author
Figuerola, Jordi
funder
Fundación La Caixa
funder
Regional Government of Andalusia (España)
funder
Ministerio de Ciencia e Innovación (España)
funder
Instituto de Salud Carlos III
funder
Agencia Estatal de Investigación (España)
funder
Consejo Superior de Investigaciones Científicas (España)
funder
Unión Europea. Comisión Europea. 7 Programa Marco
funder
Unión Europea. Comisión Europea. H2020
2025-03-26T09:29:09Z
2025-03-26T09:29:09Z
2024-12
Magallanes S, Llorente F, Ruiz-López MJ, Puente JM, Ferraguti M, Gutiérrez-López R, Soriguer R, Aguilera-Sepúlveda P, Fernández-Delgado R, Jímenez-Clavero MÁ, Figuerola J. Warm winters are associated to more intense West Nile virus circulation in southern Spain. Emerg Microbes Infect. 2024 Dec;13(1):2348510.
10.1080/22221751.2024.2348510
2222-1751
Emerging microbes and infections
38686545
https://hdl.handle.net/20.500.12105/26573
West Nile virus (WNV) is the most widely distributed mosquito-borne flavivirus in the world. This flavivirus can infect humans causing in some cases a fatal neurological disease and birds are the main reservoir hosts. WNV is endemic in Spain, and human cases have been reported since 2004. Although different studies analyse how climatic conditions can affect the dynamics of WNV infection, very few use long-term datasets. Between 2003 and 2020 a total of 2,724 serum samples from 1,707 common coots (Fulica atra) were analysed for the presence of WNV-specific antibodies. Mean (SD) annual seroprevalence was 24.67% (0.28) but showed high year-to-year variations ranging from 5.06% (0.17) to 68.89% (0.29). Significant positive correlations (p < 0.01) were observed between seroprevalence and maximum winter temperature and mean spring temperature. The unprecedented WNV outbreak in humans in the south of Spain in 2020 was preceded by a prolonged period of escalating WNV local circulation. Given current global and local climatic trends, WNV circulation is expected to increase in the next decades. This underscores the necessity of implementing One Health approaches to reduce the risk of future WNV outbreaks in humans. Our results suggest that higher winter and spring temperatures may be used as an early warning signal of more intense WNV circulation among wildlife in Spain, and consequently highlight the need of more intense vector control and surveillance in human inhabited areas.
eng
Arboviruses
Birds
Emerging infectious diseases
Long-term surveillance
One health
Warm winters are associated to more intense West Nile virus circulation in southern Spain
research article
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URL
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application/pdf
WarmWintersAssociatedWestNileVirus_2024.pdf
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https://repisalud.isciii.es/bitstreams/f042963b-3fa6-46f3-ae7b-0c0716187e9a/download
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Supplementary_WarmWintersAssociatedWestNileVirus_2024.pdf