2026-06-14T05:06:38Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/265332025-12-18T13:00:02Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
00925njm 22002777a 4500
dc
Fernandez-Garcia, Maria Dolores
author
Camacho, Juan
author
Díez-Fuertes, Francisco
author
Ruiz de Pedro, Estrella
author
Garcia-Ibañez, Nerea
author
Navascués, Ana
author
Berengua, Carla
author
Antequera-Rodriguez, Pedro
author
Ruiz-García, Montserrat
author
Pastor-Fajardo, Maria Teresa
author
Cabrerizo, Maria
author
2025-02
Enterovirus (EV)-C105 is a rare genotype not previously detected in Spain. Between 2019 and 2024, we detected EV-C105 in respiratory samples of five patients, through routine EV surveillance. Three cases had respiratory illness and two were hospitalised for neurological illness. Four of the five sequenced strains belonged to an emerging clade (C1), defined by four novel nonsynonymous mutations in key antigenic epitopes. We recommend reinforced clinical awareness and EV genomic surveillance, including respiratory samples, even when symptoms are neurological.
Fernandez-Garcia MD, Camacho J, Diez-Fuertes F, Ruiz de Pedro E, García-Ibañez N, Navascués A, Berengua C, Antequera-Rodriguez P, Ruiz-García M, Pastor-Fajardo MT, Cabrerizo M. Detections of rare enterovirus C105 linked to an emerging novel clade, Spain, 2019 to 2024. Euro Surveill. 2025 Feb;30(6):2500073.
10.2807/1560-7917.ES.2025.30.6.2500073
1560-7917
1025-496X
Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin
39949321
https://hdl.handle.net/20.500.12105/26533
Enterovirus C
Acute flaccid paralysis
Molecular surveillance
Detections of rare enterovirus C105 linked to an emerging novel clade, Spain, 2019 to 2024