2026-06-14T03:51:42Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/264902025-12-18T13:00:37Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19609col_20.500.12105_16977
Repisalud
author
Seijas-Pereda, Laura
author
Carmena, David
author
Rescalvo-Casas, Carlos
author
Hernando-Gozalo, Marcos
author
Prieto-Pérez, Laura
author
Cuadros-González, Juan
author
Pérez-Tanoira, Ramón
2025-03-17T09:22:27Z
2025-03-17T09:22:27Z
2024-08-17
Seijas-Pereda L, Carmena D, Rescalvo-Casas C, Hernando-Gozalo M, Prieto-Pérez L, Cuadros-González J, Pérez-Tanoira R. Global Dynamics of Gastrointestinal Colonisations and Antimicrobial Resistance: Insights from International Travellers to Low- and Middle-Income Countries. Trop Med Infect Dis. 2024 Aug 17;9(8):182.
10.3390/tropicalmed9080182
2414-6366
Tropical medicine and infectious disease
39195620
https://hdl.handle.net/20.500.12105/26490
Gastrointestinal microorganism resistance and dissemination are increasing, partly due to international travel. This study investigated gastrointestinal colonisations and the acquisition of antimicrobial resistance (AMR) genes among international travellers moving between Spain and low- and middle-income countries (Peru and Ethiopia). We analysed 102 stool samples from 51 volunteers collected before and after travel, revealing significantly higher rates of colonisation by both bacteria and protists upon return. Diarrhoeagenic strains of were the most notable microorganism detected using RT-PCR with the Seegene Allplex™ Gastrointestinal Panel Assays. A striking prevalence of β-lactamase resistance genes, particularly the TEM gene, was observed both before and after travel. No significant differences in AMR genes were found between the different locations. These findings highlight the need for rigorous surveillance and preventive strategies, as travel does not significantly impact AMR gene acquisition but does affect microbial colonisations. This study provides valuable insights into the intersection of gastrointestinal microorganism acquisition and AMR in international travellers, underscoring the need for targeted interventions and increased awareness.
eng
Escherichia coli (E. coli)
beta-lactamase genes (ESBL)
Colonisation patterns
Diarrhoeagenic strains
Gastrointestinal microorganisms
Infection control
Global Dynamics of Gastrointestinal Colonisations and Antimicrobial Resistance: Insights from International Travellers to Low- and Middle-Income Countries
research article
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GlobalDynamicsGastrointestinalColonisations_2024.pdf