2026-07-22T03:38:00Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/261952025-12-18T12:55:54Zcom_20.500.12105_19586com_20.500.12105_2202col_20.500.12105_19587
Repisalud
author
López, J A
author
Bustos, R
author
Orvell, C
author
Berois, M
author
Arbiza, J
author
García-Barreno, B
author
Melero, J A
2025-01-29T14:32:19Z
2025-01-29T14:32:19Z
1998-08
J Virol. 1998 Aug;72(8):6922-8.
Journal of Virology
9658147
https://hdl.handle.net/20.500.12105/26195
New series of escape mutants of human respiratory syncytial virus were prepared with monoclonal antibodies specific for the fusion (F) protein. Sequence changes selected in the escape mutants identified two new antigenic sites (V and VI) recognized by neutralizing antibodies and a group-specific site (I) in the F1 chain of the F molecule. The new epitopes, and previously identified antigenic sites, were incorporated into a refined prediction of secondary-structure motifs to generate a detailed antigenic map of the F glycoprotein.
eng
Antigenic structure of human respiratory syncytial virus fusion glycoprotein.
research article
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URL
https://repisalud.isciii.es/bitstreams/e277abf8-0fc9-476a-ad2c-85b9b1b94712/download
File
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c1d25d69f0dc6435e05551dbf52f6698
827100
application/pdf
Antigenic structure of human_J Virol_1998 .pdf