2026-06-14T03:45:14Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/261442025-12-18T12:56:20Zcom_20.500.12105_2173com_20.500.12105_2051col_20.500.12105_19597
Repisalud
author
Bueno, Clara
author
Torres-Ruiz, Raul
author
Velasco-Hernandez, Talia
author
Molina, Oscar
author
Petazzi, Paolo
author
Martinez, Alba
author
Rodriguez, Virginia
author
Vinyoles, Meritxell
author
Cantilena, Sandra
author
Williams, Owen
author
Vega-Garcia, Nerea
author
Rodriguez Perales, Sandra
author
Segovia, Jose C
author
Quintana-Bustamante, Oscar
author
Roy, Anindita
author
Meyer, Claus
author
Marschalek, Rolf
author
Smith, Alastair L
author
Milne, Thomas A
author
Fraga, Mario F
author
Tejedor, Juan Ramón
author
Menéndez, Pablo
funder
UK Research & Innovation (UKRI)
funder
Medical Research Council UK (MRC)
2025-01-27T10:31:57Z
2025-01-27T10:31:57Z
2023-11-16
Blood . 2023 Nov 16;142(20):1752-1756.
Blood
37756522
https://hdl.handle.net/20.500.12105/26144
Cellular ontogeny and MLL breakpoint site influence the capacity of MLL-edited CD34+ hematopoietic cells to initiate and recapitulate infant patients' features in pro-B-cell acute lymphoblastic leukemia (B-ALL). We provide key insights into the leukemogenic determinants of MLL-AF4+ infant B-ALL.
eng
ACUTE LEUKEMIAS
RECOMBINOME
BREAKPOINTS
BIOLOGY
MLL-AF4
A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features.
letter to the editor
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URL
https://repisalud.isciii.es/bitstreams/7f04b553-b20b-44d8-b7a6-57f4607498b8/download
File
MD5
79ecf5f9f37f43f29b257e27abdef794
963797
application/pdf
ahumangenomeeditingbased-2023.pdf