2026-08-05T12:20:06Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/261442025-12-18T12:56:20Zcom_20.500.12105_2173com_20.500.12105_2051col_20.500.12105_19597

00925njm 22002777a 4500 dc Bueno, Clara author Torres-Ruiz, Raul author Velasco-Hernandez, Talia author Molina, Oscar author Petazzi, Paolo author Martinez, Alba author Rodriguez, Virginia author Vinyoles, Meritxell author Cantilena, Sandra author Williams, Owen author Vega-Garcia, Nerea author Rodriguez Perales, Sandra author Segovia, Jose C author Quintana-Bustamante, Oscar author Roy, Anindita author Meyer, Claus author Marschalek, Rolf author Smith, Alastair L author Milne, Thomas A author Fraga, Mario F author Tejedor, Juan Ramón author Menéndez, Pablo author 2023-11-16 Cellular ontogeny and MLL breakpoint site influence the capacity of MLL-edited CD34+ hematopoietic cells to initiate and recapitulate infant patients' features in pro-B-cell acute lymphoblastic leukemia (B-ALL). We provide key insights into the leukemogenic determinants of MLL-AF4+ infant B-ALL. Blood . 2023 Nov 16;142(20):1752-1756. Blood 37756522 https://hdl.handle.net/20.500.12105/26144 ACUTE LEUKEMIAS RECOMBINOME BREAKPOINTS BIOLOGY MLL-AF4 A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features.