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oai:repisalud.isciii.es:20.500.12105/259922025-12-18T13:00:11Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Negredo, Anabel author Habela, Miguel Ángel author Ramirez de Arellano, Eva author Díez-Fuertes, Francisco author Lasala, Fátima author López, Pablo author Lasala, Fátima author Sarriá, Ana author Labiod, Nuria author Calero-Bernal, Rafael author Arenas, Miguel author Tenorio, Antonio author Estrada-Peña, Agustín author Sánchez-Seco, María Paz author 2019-06 During 2011-2015, we conducted a Crimean-Congo hemorrhagic fever virus (CCHFV) survey in captured ticks that were feeding mainly on wild and domestic ungulates in Spain, where presence of this virus had been reported previously. We detected CCHFV RNA in Hyalomma lusitanicum and H. marginatum ticks for 3 of the 5 years. The rate of infected ticks was 2.78% (44/1,579), which was similar to those for other countries in Europe with endemic foci for CCHFV (Kosovo, Bulgaria, and Albania). These data confirm the established spread of CCHFV into western Europe. Phylogenetic study of the small RNA segment showed Africa-3 clade as the only genotype identified, although we observed cocirculation of genetic variants during 2011 and 2015. We could not rule out genetic reassortments because of lack of sequence data for the medium and large RNA segments of the virus genome. Negredo A, Habela MÁ, Ramírez de Arellano E, Diez F, Lasala F, López P, Sarriá A, Labiod N, Calero-Bernal R, Arenas M, Tenorio A, Estrada-Peña A, Sánchez-Seco MP. Survey of Crimean-Congo Hemorrhagic Fever Enzootic Focus, Spain, 2011-2015. Emerg Infect Dis. 2019 Jun;25(6):1177-1184. 10.3201/eid2506.180877 1080-6059 1080-6040 Emerging infectious diseases 31107219 https://hdl.handle.net/20.500.12105/25992 CCHFV Crimean Congo hemorrhagic fever virus Crimean-Congo hemorrhagic fever Hyalomma spp. ticks Spain Endemic circulation Enzootic focus Molecular epidemiology survey Phylogenetic analysis Reverse transcription PCR Tick-borne infections Vector-borne infections Viruses Zoonoses Survey of Crimean-Congo Hemorrhagic Fever Enzootic Focus, Spain, 2011-2015