2026-05-01T11:52:44Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/259442025-12-18T12:59:18Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19609col_20.500.12105_16973
Repisalud
author
Oliván-Blázquez, Bárbara
author
Bona-Otal, Marta
author
Méndez-López, Fátima
author
Lerma-Irureta, David
author
García-Izuel, Paula
author
Ibáñez-Ruiz, Jesús
author
Montolío, Alberto
author
Ruiz-Herreros, María
author
Godino, Javier
author
Jimeno-Beltran, Beatriz
author
Encabo-Berzosa, María Del Mar
author
Arenaz, Izaskun
author
Medel-Martínez, Ana
author
Casado-Vicente, Verónica
author
Coiras, Mayte
author
Tellería-Orriols, Carlos
author
Schoorlemmer, Jon
author
Magallón-Botaya, Rosa
funder
Instituto de Salud Carlos III
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
funder
Unión Europea. Comisión Europea. Horizonte Europa
funder
Gobierno de Aragón (España)
funder
Instituto de Investigación Sanitaria Aragón
funder
Instituto Aragonés de Ciencias de la Salud
2025-01-07T13:32:54Z
2025-01-07T13:32:54Z
2024-09-20
Oliván-Blázquez B, Bona-Otal M, Méndez-López F, Lerma-Irureta D, García-Izuel P, Ibáñez-Ruiz J, Montolío A, Ruiz-Herreros M, Godino J, Jimeno-Beltran B, Encabo-Berzosa MDM, Arenaz I, Medel-Martínez A, Casado-Vicente V, Coiras M, Tellería-Orriols C, Schoorlemmer J, Magallón-Botaya R. Characterization model of the post COVID-19 condition based on immunological, biochemical, and cytokine markers. iScience. 2024 Aug 30;27(9):110839.
10.1016/j.isci.2024.110839
2589-0042
iScience
39318534
https://hdl.handle.net/20.500.12105/25944
Post-coronavirus disease condition (PCC) continues to affect many people globally, yet there remains a lack of diagnostic biomarkers to distinguish PCC from those recovered from acute COVID-19. This study compared biomarkers between two age- and gender-matched groups: PCC individuals and those recovered within three months of acute COVID-19 in 2020 ( = 85 each). Biomarkers were assessed 12-24 months after initial diagnosis, examining biochemical profiles, blood cell counts, coagulation status, antibody serology, lymphocyte populations, and cytokine levels. PCC individuals exhibited significant alterations in 49 of 167 markers, including K+ levels, αGAD antibodies, antithrombin III, insulin-like growth factor-binding protein 3 (IGFBP3), and interleukin-10 (IL-10). A panel of αGAD, IL-10, potassium levels, and CD16CD56 cell presence distinguished PCC individuals from recovered patients with >88% accuracy and <92% precision.
eng
Biochemistry
Immunology
Virology
Characterization model of the post COVID-19 condition based on immunological, biochemical, and cytokine markers
research article
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CharacterizationModelPostCOVID-19_Condition_2024.pdf
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https://repisalud.isciii.es/bitstreams/54fffe5c-69d3-4b7a-8b97-0e98960ca615/download
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Supplementary_CharacterizationModelPostCOVID-19_Condition_2024.pdf