2026-06-14T03:44:53Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/259292025-12-18T12:58:00Zcom_20.500.12105_19586com_20.500.12105_2202col_20.500.12105_19587

00925njm 22002777a 4500 dc Celia Martín‐Morales author Sofia Caspani author Manuel Desco author Célia Tavares de Sousa author María Victoria Gómez‐Gaviro author 2024-10-08 This review offers a comprehensive exploration of optimized drug delivery systems tailored for controlled release and their crucial role in addressing cerebrovascular diseases. Through an in-depth analysis, various controlled release methods, including nanoparticles, liposomes, hydrogels, and other emerging technologies are examined. Highlighting the importance of precise drug targeting, it is delved into the underlying mechanisms of these delivery systems and their potential to improve therapeutic outcomes while minimizing adverse effects. Additionally, the specific applications of these optimized drug delivery systems in treating cerebrovascular disorders such as ischemic stroke, cerebral aneurysms, and intracranial hemorrhage are discussed. By shedding light on the advancements in drug delivery techniques and their implications in cerebrovascular medicine, this review offers valuable insights into the future of therapeutic interventions in neurology. Advanced Therapeutics, 2024 doi: 10.1002/adtp.202400239 10.1002/adtp.202400239 2366-3987 Advanced Therapeutics https://hdl.handle.net/20.500.12105/25929 Controlled Drug Release Systems for Cerebrovascular Diseases