2026-04-29T04:52:20Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/258802025-12-18T12:57:22Zcom_20.500.12105_2327com_20.500.12105_2290col_20.500.12105_16991
Repisalud
author
Garcia-Carbonero, R
author
Matute Teresa, F
author
Mercader-Cidoncha, E
author
Mitjavila-Casanovas, M
author
Robledo Batanero, Mercedes
author
Tena, I
author
Alvarez-Escola, C
author
ArÃstegui, M
author
Bella-Cueto, M R
author
Ferrer-Albiach, C
author
Hanzu, F A
2024-12-13T13:38:54Z
2024-12-13T13:38:54Z
2021-10
Clin Transl Oncol . 2021 Oct;23(10):1995-2019.
https://hdl.handle.net/20.500.12105/25880
33959901
Clinical Translational Oncology
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors that arise from chromaffin cells of the adrenal medulla and the sympathetic/parasympathetic neural ganglia, respectively. The heterogeneity in its etiology makes PPGL diagnosis and treatment very complex. The aim of this article was to provide practical clinical guidelines for the diagnosis and treatment of PPGLs from a multidisciplinary perspective, with the involvement of the Spanish Societies of Endocrinology and Nutrition (SEEN), Medical Oncology (SEOM), Medical Radiology (SERAM), Nuclear Medicine and Molecular Imaging (SEMNIM), Otorhinolaryngology (SEORL), Pathology (SEAP), Radiation Oncology (SEOR), Surgery (AEC) and the Spanish National Cancer Research Center (CNIO). We will review the following topics: epidemiology; anatomy, pathology and molecular pathways; clinical presentation; hereditary predisposition syndromes and genetic counseling and testing; diagnostic procedures, including biochemical testing and imaging studies; treatment including catecholamine blockade, surgery, radiotherapy and radiometabolic therapy, systemic therapy, local ablative therapy and supportive care. Finally, we will provide follow-up recommendations.
eng
Diagnosis
Genetic counseling
Guidelines
Multidisciplinary
Paraganglioma
Pheochromocytoma
Treatment
Multidisciplinary practice guidelines for the diagnosis, genetic counseling and treatment of pheochromocytomas and paragangliomas.
research article
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URL
https://repisalud.isciii.es/bitstreams/193c0072-74a1-4185-b21b-83210c76a3d2/download
File
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01219a2a9625fec27a1a9bf32ad7daba
2176257
application/pdf
Multidisciplinarypracticeguidelines-2021.pdf