2026-04-29T04:52:15Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/258802025-12-18T12:57:22Zcom_20.500.12105_2327com_20.500.12105_2290col_20.500.12105_16991

00925njm 22002777a 4500 dc Garcia-Carbonero, R author Matute Teresa, F author Mercader-Cidoncha, E author Mitjavila-Casanovas, M author Robledo Batanero, Mercedes author Tena, I author Alvarez-Escola, C author Arístegui, M author Bella-Cueto, M R author Ferrer-Albiach, C author Hanzu, F A author 2021-10 Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors that arise from chromaffin cells of the adrenal medulla and the sympathetic/parasympathetic neural ganglia, respectively. The heterogeneity in its etiology makes PPGL diagnosis and treatment very complex. The aim of this article was to provide practical clinical guidelines for the diagnosis and treatment of PPGLs from a multidisciplinary perspective, with the involvement of the Spanish Societies of Endocrinology and Nutrition (SEEN), Medical Oncology (SEOM), Medical Radiology (SERAM), Nuclear Medicine and Molecular Imaging (SEMNIM), Otorhinolaryngology (SEORL), Pathology (SEAP), Radiation Oncology (SEOR), Surgery (AEC) and the Spanish National Cancer Research Center (CNIO). We will review the following topics: epidemiology; anatomy, pathology and molecular pathways; clinical presentation; hereditary predisposition syndromes and genetic counseling and testing; diagnostic procedures, including biochemical testing and imaging studies; treatment including catecholamine blockade, surgery, radiotherapy and radiometabolic therapy, systemic therapy, local ablative therapy and supportive care. Finally, we will provide follow-up recommendations. Clin Transl Oncol . 2021 Oct;23(10):1995-2019. https://hdl.handle.net/20.500.12105/25880 33959901 Clinical Translational Oncology Diagnosis Genetic counseling Guidelines Multidisciplinary Paraganglioma Pheochromocytoma Treatment Multidisciplinary practice guidelines for the diagnosis, genetic counseling and treatment of pheochromocytomas and paragangliomas.