2026-08-29T14:15:15Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/258562025-12-18T12:57:00Zcom_20.500.12105_2327com_20.500.12105_2290col_20.500.12105_16991

00925njm 22002777a 4500 dc Miarka, Lauritz author Valiente, Manuel author 2021-11 Modeling of metastatic disease in animal models is a critical resource to study the complexity of this multi-step process in a relevant system. Available models of metastatic disease to the brain are still far from ideal but they allow to address specific aspects of the biology or mimic clinically relevant scenarios. We not only review experimental models and their potential improvements but also discuss specific answers that could be obtained from them on unsolved aspects of clinical management. Neurooncol Adv . 2021 Nov 27;3(Suppl 5):v144-v156. Neurooncol Adv 34859241 https://hdl.handle.net/20.500.12105/25856 brain metastasis experimental models therapy treatment toxicity Animal models of brain metastasis.