2026-07-21T08:08:48Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/255012025-12-18T12:55:47Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Gonzalez, Estela
author
Molina, Ricardo
author
Aldea, Irene
author
Iriso, Andrés
author
Tello, Ana
author
Jimenez, Maribel
funder
Comunidad de Madrid (España)
funder
Colegio Oficial de Veterinarios de Madrid (España)
funder
Colegio Oficinal de Biólogos de la Comunidad de Madrid (España)
2024-11-14T10:18:22Z
2024-11-14T10:18:22Z
2020-05
Transbound Emerg Dis. 2020 May;67(3):1393-1400.
10.1111/tbed.13464
1865-1682
1865-1674
Transboundary and emerging diseases
31885197
https://hdl.handle.net/20.500.12105/25501
Phlebotomine sand flies are the only known vectors of Leishmania spp. protozoan which causes leishmaniasis in 98 countries. In Spain, 11 sand fly species are described, but only Phlebotomus perniciosus and Phlebotomus ariasi are proven vectors of the disease. On the other hand, Sergentomyia minuta is one of the most abundant and ubiquitous sand flies in this territory, although scarce information is available about this species. Sand flies from this genus are known for their preference to feed on cold-blooded animals and are traditionally involved in the transmission of reptile Leishmania. However, studies have suggested that Sergentomyia spp. could be implicated in the transmission of human pathogenic Leishmania. This study analyses blood meal preferences and Leishmania sp. infection of S. minuta sand flies from the largest human leishmaniasis outbreak in Europe. Sand flies were collected during entomological surveillance carries out from 2012 to 2017 in the active season of these dipterans, from May to October. Molecular detection of Leishmania spp. showed 68 positive specimens of S. minuta out of 377 (18%). The analysis of blood meal preferences by amplification of 359 bp fragment of cytochrome b gene revealed that blood preference of S. minuta is not only limited to reptiles, but they also feed on mammals, including humans. Results suggest the presence of a Leishmania sp., related to Leishmania tarentolae, cycle in S. minuta from the studied area. Although there is no evidence about its incrimination in the L. infantum transmission more investigation is needed to elucidate the intravectorial cycle of Leishmania spp. in S. minuta sand flies, their feeding behaviour and their potential contribution in Leishmania spp. epidemiology in the country.
eng
Sergentomyia minuta
Leishmania spp.
Spain
Feeding behaviour
Human leishmaniasis outbreak
Vector competence
Leishmania sp. detection and blood-feeding behaviour of Sergentomyia minuta collected in the human leishmaniasis focus of southwestern Madrid, Spain (2012-2017)
research article
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URL
https://repisalud.isciii.es/bitstreams/e142f8c5-0cd1-4f1d-b38b-141f61c713d5/download
File
MD5
6712543eb281983ee526409b291a255d
1184440
application/pdf
Leishmania_spp_DetectionBlood-feeding_2020.pdf
URL
https://repisalud.isciii.es/bitstreams/c9190c0a-4025-4b78-b003-2e3ae75dc429/download
File
MD5
d6e6b3c2291f87dc48c36b4c45afa239
2024920
image/tiff
Figs1_Leishmania_spp_DetectionBlood-feeding_2020.tif