2026-04-29T04:09:47Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/251732025-12-18T13:00:43Zcom_20.500.12105_2173com_20.500.12105_2051col_20.500.12105_19597
Repisalud
author
Gómez-Aleza, C
author
González-Suárez, E
funder
Unión Europea. Comisión Europea. European Research Council (ERC)
2024-10-16T12:06:33Z
2024-10-16T12:06:33Z
2021-05-14
Oncoimmunology . 2021 May 14;10(1):1923156.
https://hdl.handle.net/20.500.12105/25173
34026334
Oncoimmunology
RANK signaling in mouse mammary tumor cells exerts an immunosuppressive environment by promoting the infiltration of pro-tumorigenic neutrophils and preventing CD8 T cell recruitment. Single-agent denosumab led to an increased tumor immune infiltration by lymphocytes and CD8 + T cells in breast cancer patients, supporting the immunomodulatory role of RANK signaling.
eng
RANK
RANKL
breast cancer
denosumab
immunotherapy
Inhibition of RANK signaling as a potential immunotherapy in breast cancer.
research article
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URL
https://repisalud.isciii.es/bitstreams/ada984a4-1bbd-4831-940d-af194900a4fc/download
File
MD5
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application/pdf
InhibitionofRANKsignaling_2021.pdf
URL
https://repisalud.isciii.es/bitstreams/e225b624-109c-4389-90c1-ba0b256432ab/download
File
MD5
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text/plain
InhibitionofRANKsignaling_2021.pdf.txt