2026-05-01T11:52:45Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/250852025-12-18T13:00:15Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_19609col_20.500.12105_16967

00925njm 22002777a 4500 dc Díez Galán, María Del Mar author Redondo-Bravo, Lidia author Gomez-Barroso, Diana author Herrera-Leon, Laura author Amillategui Dos Santos, Rocío author Gómez-Castellá, Javier author Herrador, Zaida author Spanish Working Group on Tuberculosis author Díez Galán, María Del Mar author Redondo-Bravo, Lidia author Gómez-Castellá, Javier author Spanish Working Group on Tuberculosis author 2024-03-20 Tuberculosis (TB) remains a global leading cause of death, necessitating an investigation into its unequal distribution. Sun exposure, linked to vitamin D (VD) synthesis, has been proposed as a protective factor. This study aimed to analyse TB rates in Spain over time and space and explore their relationship with sunlight exposure. An ecological study examined the associations between rainfall, sunshine hours, and TB incidence in Spain. Data from the National Epidemiological Surveillance Network (RENAVE in Spanish) and the Spanish Meteorological Agency (AEMET in Spanish) from 2012 to 2020 were utilized. Correlation and spatial regression analyses were conducted. Between 2012 and 2020, 43,419 non-imported TB cases were reported. A geographic pattern (north-south) and distinct seasonality (spring peaks and autumn troughs) were observed. Sunshine hours and rainfall displayed a strong negative correlation. Spatial regression and seasonal models identified a negative correlation between TB incidence and sunshine hours, with a four-month lag. A clear spatiotemporal association between TB incidence and sunshine hours emerged in Spain from 2012 to 2020. VD levels likely mediate this relationship, being influenced by sunlight exposure and TB development. Further research is warranted to elucidate the causal pathway and inform public health strategies for improved TB control. Epidemiol Infect. 2024 Mar 20:152:e58. 10.1017/S0950268824000499 1469-4409 0950-2688 Epidemiology and infection 38505884 https://hdl.handle.net/20.500.12105/25085 Spain Time series Vitamin D Geospatial analysis Solar radiation Tuberculosis The impact of meteorological factors on tuberculosis incidence in Spain: a spatiotemporal analysis