2026-05-20T04:01:37Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/238362024-11-28T15:37:26Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16959col_20.500.12105_16961col_20.500.12105_16962col_20.500.12105_16967col_20.500.12105_16968col_20.500.12105_16969col_20.500.12105_16977col_20.500.12105_16982col_20.500.12105_16983col_20.500.12105_16989
Repisalud
author
Baenas, I
author
Camacho-Barcia, L
author
Granero, R
author
Razquin, C
author
Corella, D
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Gómez-Martínez, Carlos
author
Castañer-Niño, O
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Martínez, JA
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Alonso-Gómez, ÁM
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Wärnberg, Julia
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Vioque, Jesus
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Romaguera, Dora
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López-Miranda, J
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Estruch, R
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Tinahones, Francisco J
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Lapetra, J
author
Serra-Majem, Lluis
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Cano-Ibáñez, N
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Tur, Josep A
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Martín-Sánchez, V
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Pintó, X
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Gaforio, J J
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Matía-Martín, P
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Vidal, Josep
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Vazquez, Clotilde
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Daimiel, L
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Ros, Emilio
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Jiménez-Murcia, S
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Dalsgaard, S
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Garcia-Arellano, A
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Babio, N
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Sorli, Jose V
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Lassale, C
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García-de-la-Hera, M
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Gómez-García, E
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Zulet, MA
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Konieczna, Jadwiga
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Martín-Peláez, S
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Tojal-Sierra, Lucas
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Basterra-Gortari, FJ
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de Las Heras-Delgado, S
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Portoles, O
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Muñoz-Pérez, MÁ
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Arenas-Larriva, AP
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Compañ-Gabucio, L
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Eguaras, S
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Shyam, Sangeetha
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Fitó, M
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Baños, RM
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Salas-Salvado, Jordi
author
Fernández-Aranda, F
2024-10-09T07:09:20Z
2024-10-09T07:09:20Z
2024-01-13
Baenas I, Camacho-Barcia L, Granero R, Razquin C, Corella D, Gómez-Martínez C, et al. Association between type 2 diabetes and depressive symptoms after a 1-year follow-up in an older adult Mediterranean population. J Endocrinol Invest. 2024 Jan 13.
10.1007/s40618-023-02278-y10.1007/s40618-023-02278-y
1720-8386
Journal of endocrinological investigation
https://hdl.handle.net/20.500.13003/20138
38218741
L2027900272
2-s2.0-85182212511
https://hdl.handle.net/20.500.12105/23836
1142489700002
Objectives: To examine the cross-sectional association between baseline depressive symptoms and the presence of type 2 diabetes (T2D), and its association with glycated hemoglobin (HbA1c) and other metabolic variables, and the prospective association of depressive symptoms and HbA1c after 1 year of follow-up. Methods: n = 6224 Mediterranean older adults with overweight/obesity and metabolic syndrome (48% females, mean age 64.9 ± 4.9 years) were evaluated in the framework of the PREDIMED-Plus study cohort. Depressive symptoms were assessed using the Beck Depression Inventory-II and HbA1c was used to measure metabolic control. Results: The presence of T2D increased the likelihood of higher levels of depressive symptoms (χ2 = 15.84, p = 0.001). Polynomial contrast revealed a positive linear relationship (χ2 = 13.49, p = 0.001), the higher the depressive symptoms levels, the higher the prevalence of T2D. Longitudinal analyses showed that the higher baseline depressive symptoms levels, the higher the likelihood of being within the HbA1c ≥ 7% at 1-year level (Wald-χ2 = 24.06, df = 3, p < .001, for the full adjusted model). Additionally, depressive levels at baseline and duration of T2D predicted higher HbA1c and body mass index, and lower physical activity and adherence to Mediterranean Diet at 1 year of follow-up. Conclusions: This study supports an association between T2D and the severity of depressive symptoms, suggesting a worse metabolic control from mild severity levels in the short-medium term, influenced by lifestyle habits related to diabetes care. Screening for depressive symptoms and a multidisciplinary integrative therapeutic approach should be ensured in patients with T2D.
eng
Association between type 2 diabetes and depressive symptoms after a 1-year follow-up in an older adult Mediterranean population
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