2026-04-29T01:00:01Zhttps://repisalud.isciii.es/rest/oai/request
oai:repisalud.isciii.es:20.500.12105/237882024-11-29T07:08:57Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
Repisalud author Viver, T author López-Causapé, Carla author Fraile-Ribot, Pablo A author Pérez-Mazón, Carmen author López-Solé, Dolores author Jiménez-Guerra, Gemma author Taltavull, Biel author López-López, Aránzazu 2024-10-09T06:36:29Z 2024-10-09T06:36:29Z 2023-10-23 Viver T, López-Causapé C, Ribot-Fraile P, Pérez-Mazón C, López-Solé D, Jiménez-Guerra G, et al. The molecular epidemiology of SARS-CoV-2 in the Pityusic Islands shows multiple introductions and fast replacements of variants in a touristic worldwide hot spot. Sci Rep. 2023 Oct 23;13(1):18053. https://hdl.handle.net/20.500.13003/20015 https://hdl.handle.net/20.500.12105/23788 37872265 10.1038/s41598-023-44668-5 2045-2322 Scientific reports 1087271600002 L642594721 The public health emergency caused by the Covid-19 outbreak in March 2020 encouraged worldwide initiatives to monitor the genetic diversity and features of the SARS-CoV-2 circulating variants, mainly based on the genomic surveillance. However, due to the impossibility to carry out extensive sequencing in resource-limited hospitals, other PCR-based strategies could be applied to efficiently monitor the circulating variants without the need to greatly expand the sequencing capacity. In our case, overpassing the technical limitations inherent to a second level hospital, we were able to characterize the weekly distribution of SARS-CoV-2 by the RT-qPCR amplification patterns visualization, single nucleotide polymorphism genotyping, and sequencing of randomly selected samples. All these molecular approaches allowed us to trace the epidemiology of SARS-CoV-2 viruses circulating in Ibiza and Formentera (Balearic Islands, Spain) during the third to the sixth pandemic waves (January 2021-July 2022), in which three major lineages that were considered as VOCs (Alpha, Delta, and Omicron), and many other non-VOC variants were detected and tracked. eng The molecular epidemiology of SARS-CoV-2 in the Pityusic Islands shows multiple introductions and fast replacements of variants in a touristic worldwide hot spot research article