2026-05-01T11:52:45Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/237152024-11-29T01:45:51Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967col_20.500.12105_16973
Repisalud
author
Garcia Toro, Mauro
author
Aguilar-Latorre, Alejandra
author
Garcia, Aurora
author
Navarro-Guzmán, Capilla
author
Gervilla Garcia, Elena
author
Seguí, Andrea
author
Gazquez, Francisco
author
Marino, Jose Antonio
author
Gomez-Juanes, Rocío
author
Serrano-Ripoll, Maria Jesus
author
Oliván-Blázquez, Bárbara
author
Garcia-Campayo, Javier
author
Maloney, Shannon
author
Montero-Marin, Jesús
2024-10-09T06:35:14Z
2024-10-09T06:35:14Z
2023
Garcia-Toro M, Aguilar-Latorre A, Garcia A, Navarro-Guzmán C, Gervilla E, Seguí A, et al. Mindfulness skills and experiential avoidance as therapeutic mechanisms for treatment-resistant depression through mindfulness-based cognitive therapy and lifestyle modification. Front Psychol. 2023;14:1008891.
10.3389/fpsyg.2023.1008891
1664-1078
Frontiers in psychology
https://hdl.handle.net/20.500.13003/19334
36968708
2-s2.0-85150714005
https://hdl.handle.net/20.500.12105/23715
954728500001
Background/objective: The COVID-19 pandemic and consequent physical distancing has made it difficult to provide care for those with Treatment-Resistant Depression (TRD). As a secondary analysis of a clinical trial, the aim of this study was to explore potential mechanisms through which three online-delivered approaches, added to treatment as usual, improve depressive symptoms in TRD patients. Methods: The three approaches included (a) Minimal Lifestyle Intervention (MLI), (b) Mindfulness-Based Cognitive Therapy (MBCT), and (c) Lifestyle Modification Program (LMP). Sixty-six participants with TRD completed assessments pre-post intervention (mindfulness skills [FFMQ]; self-compassion [SCS]; and experiential avoidance [AAQ-II]) and pre-intervention to follow-up (depressive symptoms [BDI-II]). Data were analyzed using within-subjects regression models to test mediation. Results: Mindfulness skills mediated the effect of MBCT on depressive symptoms (ab = -4.69, 95% CI = -12.93 to-0.32), whereas the lack of experiential avoidance mediated the effect of LMP on depressive symptoms (ab = -3.22, 95% CI = -7.03 to-0.14). Conclusion: Strengthening mindfulness skills and decreasing experiential avoidance may promote recovery in patients with TRD, MBCT, and LMP have demonstrated that they may help increase mindfulness skills and decrease experiential avoidance, respectively. Future work will need to unpick the components of these interventions to help isolate active ingredients and increase optimization.
eng
Mindfulness skills and experiential avoidance as therapeutic mechanisms for treatment-resistant depression through mindfulness-based cognitive therapy and lifestyle modification
research article