2026-04-29T04:09:08Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/236662024-11-28T20:42:03Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
Repisalud
author
Amengual-Tugores, Andreu Miquel
author
Ráez-Meseguer, Carmen
author
Forteza-Genestra, Maria Antónia
author
Monjo, Marta
author
Ramis, Joana Maria
2024-10-09T06:34:22Z
2024-10-09T06:34:22Z
2023-02-18
Amengual-Tugores AM, Ráez-Meseguer C, Forteza-Genestra MA, Monjo M, Ramis JM. Extracellular Vesicle-Based Hydrogels for Wound Healing Applications. Int J Mol Sci. 2023 Feb 18;24(4):4104.
https://hdl.handle.net/20.500.13003/18921
https://hdl.handle.net/20.500.12105/23666
36835516
10.3390/ijms24044104
1422-0067
International journal of molecular sciences
2-s2.0-85149053727
944992800001
L2021826258
Hydrogels and extracellular vesicle-based therapies have been proposed as emerging therapeutic assets in wound closure. The combination of these elements has given good results in managing chronic and acute wounds. The intrinsic characteristics of the hydrogels in which the extracellular vesicles (EVs) are loaded allow for overcoming barriers, such as the sustained and controlled release of EVs and the maintenance of the pH for their conservation. In addition, EVs can be obtained from different sources and through several isolation methods. However, some barriers must be overcome to transfer this type of therapy to the clinic, for example, the production of hydrogels containing functional EVs and identifying long-term storage conditions for EVs. The aim of this review is to describe the reported EV-based hydrogel combinations, along with the obtained results, and analyze future perspectives.
eng
Extracellular Vesicle-Based Hydrogels for Wound Healing Applications
research article