2026-07-21T16:29:02Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/235512024-11-28T22:25:14Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
Repisalud
author
Alorda-Clara, Marina
author
Torrens-Mas, Margalida
author
Morla-Barcelo, Pere Miquel
author
Martinez-Bernabe, Toni
author
Sastre-Serra, Jorge
author
Roca, Pilar
author
Pons, Daniel-Gabriel
author
Oliver, Jordi
author
Reyes Moreno, Jose
2024-10-04T13:58:05Z
2024-10-04T13:58:05Z
2022-02
Alorda-Clara M, Torrens-Mas M, Morla-Barcelo PM, Martinez-Bernabe T, Sastre-Serra J, Roca P, et al. Use of Omics Technologies for the Detection of Colorectal Cancer Biomarkers. Cancers. 2022 Feb;14(3):817.
10.3390/cancers14030817
2072-6694
Cancers
https://hdl.handle.net/20.500.13003/19895
35159084
L2015562896
2-s2.0-85124365872
https://hdl.handle.net/20.500.12105/23551
755562200001
Colorectal cancer (CRC) is one of the most frequently diagnosed cancers with high mortality rates, especially when detected at later stages. Early detection of CRC can substantially raise the 5-year survival rate of patients, and different efforts are being put into developing enhanced CRC screening programs. Currently, the faecal immunochemical test with a follow-up colonoscopy is being implemented for CRC screening. However, there is still a medical need to describe biomarkers that help with CRC detection and monitor CRC patients. The use of omics techniques holds promise to detect new biomarkers for CRC. In this review, we discuss the use of omics in different types of samples, including breath, urine, stool, blood, bowel lavage fluid, or tumour tissue, and highlight some of the biomarkers that have been recently described with omics data. Finally, we also review the use of extracellular vesicles as an improved and promising instrument for biomarker detection.
eng
Omics
Colorectal cancer
Extracellular vesicles
Tumour tissue
Blood
Stool
Bowel lavage fluid
Urine
Breath
Use of Omics Technologies for the Detection of Colorectal Cancer Biomarkers
review article