2026-07-22T20:06:46Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/235512024-11-28T22:25:14Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Alorda-Clara, Marina author Torrens-Mas, Margalida author Morla-Barcelo, Pere Miquel author Martinez-Bernabe, Toni author Sastre-Serra, Jorge author Roca, Pilar author Pons, Daniel-Gabriel author Oliver, Jordi author Reyes Moreno, Jose author 2022-02 Colorectal cancer (CRC) is one of the most frequently diagnosed cancers with high mortality rates, especially when detected at later stages. Early detection of CRC can substantially raise the 5-year survival rate of patients, and different efforts are being put into developing enhanced CRC screening programs. Currently, the faecal immunochemical test with a follow-up colonoscopy is being implemented for CRC screening. However, there is still a medical need to describe biomarkers that help with CRC detection and monitor CRC patients. The use of omics techniques holds promise to detect new biomarkers for CRC. In this review, we discuss the use of omics in different types of samples, including breath, urine, stool, blood, bowel lavage fluid, or tumour tissue, and highlight some of the biomarkers that have been recently described with omics data. Finally, we also review the use of extracellular vesicles as an improved and promising instrument for biomarker detection. Alorda-Clara M, Torrens-Mas M, Morla-Barcelo PM, Martinez-Bernabe T, Sastre-Serra J, Roca P, et al. Use of Omics Technologies for the Detection of Colorectal Cancer Biomarkers. Cancers. 2022 Feb;14(3):817. 10.3390/cancers14030817 2072-6694 Cancers https://hdl.handle.net/20.500.13003/19895 35159084 L2015562896 2-s2.0-85124365872 https://hdl.handle.net/20.500.12105/23551 755562200001 Omics Colorectal cancer Extracellular vesicles Tumour tissue Blood Stool Bowel lavage fluid Urine Breath Use of Omics Technologies for the Detection of Colorectal Cancer Biomarkers