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00925njm 22002777a 4500 dc Gómez-Sánchez, Leticia author Gómez-Sánchez, Marta author Lugones-Sánchez, Cristina author Rodríguez-Sánchez, Emiliano author Tamayo-Morales, Olaya author Gonzalez-Sánchez, Susana author Magallón-Botaya, Rosa author Ramírez-Manent, José Ignacio author Recio-Rodriguez, Jose I author Agudo-Conde, Cristina author García-Ortiz, Luis author Gómez-Marcos, Manuel A author 2022-11-10 mHealth technologies could help to improve cardiovascular health; however, their effect on arterial stiffness and hemodynamic parameters has not been explored to date. To evaluate the effect of a mHealth intervention, at 3 and 12 months, on arterial stiffness and central hemodynamic parameters in a sedentary population with overweight and obesity. Randomised controlled clinical trial (Evident 3 study). 253 subjects were included: 127 in the intervention group (IG) and 126 in the control group (CG). The IG subjects were briefed on the use of the Evident 3 app and a smart band (Mi Band 2, Xiaomi) for 3 months to promote healthy lifestyles. All measurements were recorded in the baseline visit and at 3 and 12 months. The carotid-femoral pulse wave velocity (cfPWV) and the central hemodynamic parameters were measured using a SphigmoCor Systemﾮ device, whereas the brachial-ankle pulse wave velocity (baPWV) and the Cardio Ankle Vascular Index (CAVI) were measured using a VaSera VS-2000ﾮ device. Of the 253 subjects who attended the initial visit, 237 (93.7%) completed the visit at 3 months of the intervention, and 217 (85.3%) completed the visit at 12 months of the intervention. At 12 months, IG showed a decrease in peripheral augmentation index (PAIx) (-3.60; 95% CI -7.22 to -0.00) and ejection duration (ED) (-0.82; 95% CI -1.36 to -0.27), and an increase in subendocardial viability ratio (SEVR) (5.31; 95% CI 1.18 to 9.44). In CG, cfPWV decreased at 3 months (-0.28 m/s; 95% CI -0.54 to -0.02) and at 12 months (-0.30 m/s, 95% CI -0.54 to -0.05), central diastolic pressure (cDBP) decreased at 12 months (-1.64 mm/Hg; 95% CI -3.19 to -0.10). When comparing the groups we found no differences between any variables analyzed. In sedentary adults with overweight or obesity, the multicomponent intervention (Smartphone app and an activity-tracking band) for 3 months did not modify arterial stiffness or the central hemodynamic parameters, with respect to the control group. However, at 12 months, CG presented a decrease of cfPWV and cDBP, whereas IG showed a decrease of PAIx and ED and an increase of SEVR. Gómez-Sánchez L, Gómez-Sánchez M, Lugones-Sánchez C, Rodríguez-Sánchez E, Tamayo-Morales O, Gonzalez-Sánchez S, et al. Long-Term Effectiveness of a Smartphone App and a Smart Band on ArterialStiffness and Central Hemodynamic Parameters in a Population with Overweight and Obesity (Evident 3 Study): Randomised Controlled Trial. Nutrients. 2022 Nov;14(22). 10.3390/nu14224758 2072-6643 Nutrients https://hdl.handle.net/20.500.13003/18790 36432446 L2020258906 2-s2.0-85143151944 https://hdl.handle.net/20.500.12105/23471 887561500001 Long-Term Effectiveness of a Smartphone App and a Smart Band on Arterial Stiffness and Central Hemodynamic Parameters in a Population with Overweight and Obesity (Evident 3 Study): Randomised Controlled Trial