2026-04-29T04:52:13Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/233852024-11-28T21:01:36Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
Repisalud
author
Mascaro, Catalina M
author
Bouzas, Cristina
author
Tur, Josep A
2024-10-04T13:16:24Z
2024-10-04T13:16:24Z
2022-01
Mascaro CM, Bouzas C, Tur JA. Association between Non-Alcoholic Fatty Liver Disease and Mediterranean Lifestyle: A Systematic Review. Nutrients. 2022 Jan;14(1):49.
https://hdl.handle.net/20.500.13003/19454
https://hdl.handle.net/20.500.12105/23385
35010923
10.3390/nu14010049
2072-6643
Nutrients
2-s2.0-85121510888
741744100001
L2015029374
Background and Aims: Non-alcoholic fatty liver disease (NAFLD) is an excessive accumulation of fat in the liver without alcohol abuse. It is linked to metabolic syndrome (MetS) and no pharmacological treatment exists. This systematic review aims to assess evidence about the effect of Mediterranean lifestyle on the prevention and reversion of NAFLD. Methods: A systematic literature search was performed in MEDLINE via Pubmed. MeSH terms used were: non-alcoholic fatty liver disease [MeSH Major Topic] AND metabolic syndrome [MeSH Term] AND (Diet, Mediterranean [MeSH Term]) OR (Exercise [MeSH Term]). (PROSPERO ID: 2021 CRD42021289495). Results: Thirteen research articles were selected and divided into two categories (four focused on Mediterranean diet and NAFLD and nine focused on Mediterranean diet, physical activity, and NAFLD). Information of clinical endpoints was based on NAFLD, as well as MetS, body mass index, fasting glycemia, obesity, cholesterol, triglycerides, transaminases, albuminuria, and hepatic steatosis, among others. All studies found beneficial associations between the clinical parameters of NAFLD/MetS and following a Mediterranean diet and regular physical activity. Conclusions: An effective treatment that prevents, and even reverses, NAFLD is to adapt lifestyle to the Mediterranean one, based on a Mediterranean diet and regular physical activity.
eng
Non-alcoholic fatty liver disease
Mediterranean diet
Physical activity
Mediterranean lifestyle
Metabolic syndrome
Association between Non-Alcoholic Fatty Liver Disease and Mediterranean Lifestyle: A Systematic Review
research article