2026-08-29T10:38:24Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/233112024-11-29T00:22:05Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Ballesteros Vizoso, Antonieta author Figueras-Castilla, Albert author Barceló Bennasar, Antonia author Raurich, Joan Maria author Argente del Castillo, Paula author Morell Garcia, Daniel author Velasco, Julio author Pérez-Bárcena, Jon author Llompart-Pou, Juan Antonio author 2021-10-29 The incidence of thyroid disfunction has not been analyzed in critically ill COVID-19 patients. Our objective was to analyze the relationship of the thyroid profile and in-hospital mortality in critically ill COVID-19 patients. This was a prospective single-center study involving critically ill COVID-19 patients admitted to the ICU of a tertiary University Hospital. Thyroid hormones were measured through drawing blood samples from a central venous catheter at ICU admission and on the fifth day. A multiple logistic regression analysis was performed to analyze the variables associated with mortality. The ability of the different thyroid hormones to predict in-hospital mortality was evaluated by calculating the receiver operating characteristics (ROCs) and the area under the curve (AUC). A total of 78 patients were included in the study at ICU admission; 72 had their thyroid profile measured at day 5. In-hospital mortality reached 29.5%. Multiple logistic regression analysis showed that variables associated with mortality were age and prior beta-blocker therapy at ICU admission and age fT4 at day 5. The AUC for in-hospital mortality predictions of fT4 at day 5 was 0.69. Thyroid responses are commonly observed in critically ill COVID-19 patients. fT4 at day 5 after ICU admission was associated with mortality. Ballesteros Vizoso MA, Castilla AF, Barceló A, Raurich JM, Argente del Castillo P, Morell-García D, et al. Thyroid Disfunction in Critically Ill COVID-19 Patients. Relationship with In-Hospital Mortality. J Clin Med. 2021;10(21):5057. 10.3390/jcm10215057 2077-0383 Journal of clinical medicine http://hdl.handle.net/20.500.13003/18647 34768580 L2014311031 2-s2.0-85118122339 https://hdl.handle.net/20.500.12105/23311 718840400001 Thyroid Disfunction in Critically Ill COVID-19 Patients. Relationship with In-Hospital Mortality