2026-04-29T04:10:00Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/232412024-11-29T08:04:09Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967col_20.500.12105_16983
Repisalud
author
Roso-Bas, Fatima
author
Alonso-Llobregat, Maria Dolores
author
Bento, Leyre
author
Sanchez-Gonzalez, Blanca
author
Herraez Balanzat, Ines
author
Garcia-Dilla, Pilar
author
Vallespir, Catalina
author
Rado, Francesca
author
Rodriguez, Raquel
author
Garcia-Pallarols, Francesc
author
Aguirre-Orue, Iratxe
author
Bargay Lleonart, Joan
author
Sampol Mayol, Antonia
author
Salar, Antonio
author
Gutierrez, Antonio
2024-09-18T06:43:34Z
2024-09-18T06:43:34Z
2021-04
Roso-Bas F, Alonso-Llobregat MD, Bento L, Sanchez-Gonzalez B, Herraez I, Garcia-Dilla P, et al. Analysis of Personality Traits in Patients with Hodgkin Lymphoma. J Clin Med. 2021 Apr;10(8):1631.
https://hdl.handle.net/20.500.13003/19440
https://hdl.handle.net/20.500.12105/23241
33921383
10.3390/jcm10081631
2077-0383
Journal of Clinical Medicine
2-s2.0-85114077965
644452300001
L2006934989
Hodgkin lymphoma (HL) is a highly-curable malignancy mostly affecting young people. As far as we know, there is no published study that has analyzed personality profiles in HL nor their potential role in lymphomagenesis, natural history, or response to treatment. We aim to explore the personality traits of HL patients, as well as the prevalence of mental disorders and suicide ideas. We retrospectively identified all alive HL patients from three centers (Son Espases and Son Llatzer University Hospitals and Hospital del Mar of Barcelona) for using NEO Five-Factor Inventory (NEO-FFI) and Personality Inventory for DSM-5 Brief Form. Patients with HL showed significantly higher neuroticism scores and lower conscientiousness, extraversion, and openness. Considering maladaptive personality traits, HL patients showed higher levels of detachment and psychoticism. All of these translated into the fact that HL patients showed more than double the prevalence of mental illnesses (41%) and more than triple the prevalence of suicidal ideation or attempts than the general population (15 and 6%, respectively). An exploratory analysis of biomarkers associated with HL personality traits showed that higher scores of neuroticism correlated with more elevated erythrocyte sedimentation rate (ESR) and red cell distribution width (RDW), suggesting a potential link between neuroticism and proinflammatory activity in HL.
eng
Five-factor model
Personality traits
Maladaptive traits
Mental disorders
Hodgkin lymphoma
Health outcomes
Inflammatory biomarkers
Analysis of Personality Traits in Patients with Hodgkin Lymphoma
research article