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oai:repisalud.isciii.es:20.500.12105/232412024-11-29T08:04:09Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967col_20.500.12105_16983

00925njm 22002777a 4500 dc Roso-Bas, Fatima author Alonso-Llobregat, Maria Dolores author Bento, Leyre author Sanchez-Gonzalez, Blanca author Herraez Balanzat, Ines author Garcia-Dilla, Pilar author Vallespir, Catalina author Rado, Francesca author Rodriguez, Raquel author Garcia-Pallarols, Francesc author Aguirre-Orue, Iratxe author Bargay Lleonart, Joan author Sampol Mayol, Antonia author Salar, Antonio author Gutierrez, Antonio author 2021-04 Hodgkin lymphoma (HL) is a highly-curable malignancy mostly affecting young people. As far as we know, there is no published study that has analyzed personality profiles in HL nor their potential role in lymphomagenesis, natural history, or response to treatment. We aim to explore the personality traits of HL patients, as well as the prevalence of mental disorders and suicide ideas. We retrospectively identified all alive HL patients from three centers (Son Espases and Son Llatzer University Hospitals and Hospital del Mar of Barcelona) for using NEO Five-Factor Inventory (NEO-FFI) and Personality Inventory for DSM-5 Brief Form. Patients with HL showed significantly higher neuroticism scores and lower conscientiousness, extraversion, and openness. Considering maladaptive personality traits, HL patients showed higher levels of detachment and psychoticism. All of these translated into the fact that HL patients showed more than double the prevalence of mental illnesses (41%) and more than triple the prevalence of suicidal ideation or attempts than the general population (15 and 6%, respectively). An exploratory analysis of biomarkers associated with HL personality traits showed that higher scores of neuroticism correlated with more elevated erythrocyte sedimentation rate (ESR) and red cell distribution width (RDW), suggesting a potential link between neuroticism and proinflammatory activity in HL. Roso-Bas F, Alonso-Llobregat MD, Bento L, Sanchez-Gonzalez B, Herraez I, Garcia-Dilla P, et al. Analysis of Personality Traits in Patients with Hodgkin Lymphoma. J Clin Med. 2021 Apr;10(8):1631. https://hdl.handle.net/20.500.13003/19440 https://hdl.handle.net/20.500.12105/23241 33921383 10.3390/jcm10081631 2077-0383 Journal of Clinical Medicine 2-s2.0-85114077965 644452300001 L2006934989 Five-factor model Personality traits Maladaptive traits Mental disorders Hodgkin lymphoma Health outcomes Inflammatory biomarkers Analysis of Personality Traits in Patients with Hodgkin Lymphoma