2026-08-29T14:15:13Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/232212024-11-28T20:37:22Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
Repisalud
author
Sarkar, Chandan
author
Mondal, Milon
author
Khanom, Bilkis
author
Hossain, Md. Monir
author
Hossain, Md. Solayman
author
Sureda Gomila, Antoni
author
Islam, Muhammad Torequl
author
Martorell, Miquel
author
Kumar, Manoj
author
Sharifi-Rad, Javad
author
Al-Harrasi, Ahmed
author
Al-Rawahi, Ahmed
2024-09-18T06:42:41Z
2024-09-18T06:42:41Z
2021-06-01
Sarkar C, Mondal M, Khanom B, Hossain MM, Hossain MS, Sureda A, et al. Heliotropium indicum L.: From Farm to a Source of Bioactive Compounds with Therapeutic Activity. Evid-Based Complement Altern Med. 2021 Jun 1;2021:9965481.
10.1155/2021/9965481
1741-4288
1741-427X
Evidence-Based Complementary and Alternative Medicine
https://hdl.handle.net/20.500.13003/19620
34158818
L2013081754
2-s2.0-85108072396
https://hdl.handle.net/20.500.12105/23221
664489700001
This study aimed to summarize the available data on the ethnomedicinal and phytopharmacological activities of Heliotropium indicum L. based on database reports. For this purpose, an up-to-date literature search was carried out in the Google Scholar, Scopus, Springer Link, Web of Science, ScienceDirect, ResearchGate, PubMed, Chem Spider, Elsevier, BioMed Central, and patent offices (e.g., USPTO, CIPO, NPI, Google patents, and Espacenet) for the published materials. The findings suggest that the plant contains many important phytochemicals, including pyrrolizidine alkaloids, indicine, echinitine, supinine, heleurine, heliotrine, lasiocarpine, acetyl indicine, indicinine, indicine N-oxide, cynoglossine, europine N-oxide, heleurine N-oxide, heliotridine Noxide, heliotrine N-oxide, heliotrine, volatile oils, triterpenes, amines, and sterols. Scientific reports revealed that the herb showed antioxidant, analgesic, antimicrobial, anticancer, antituberculosis, antiplasmodial, anticataract, antifertility, wound healing, antiinflammatory, antinociceptive, antihyperglycemic, anthelmintic, diuretic, antitussive, antiglaucoma, antiallergic, and larvicidal activity. In conclusion, in vitro studies with animal models seem to show the potential beneficial effects of H. indicum against a wide variety of disorders and as a source of phytotherapeutic compounds. However, clinical studies are necessary to confirm the effects observed in animal models, determine the toxicity of the therapeutic dose and isolate the truly bioactive components.
eng
Heliotropium indicum L.: From Farm to a Source of Bioactive Compounds with Therapeutic Activity
review article