2026-08-29T14:55:07Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/232212024-11-28T20:37:22Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Sarkar, Chandan author Mondal, Milon author Khanom, Bilkis author Hossain, Md. Monir author Hossain, Md. Solayman author Sureda Gomila, Antoni author Islam, Muhammad Torequl author Martorell, Miquel author Kumar, Manoj author Sharifi-Rad, Javad author Al-Harrasi, Ahmed author Al-Rawahi, Ahmed author 2021-06-01 This study aimed to summarize the available data on the ethnomedicinal and phytopharmacological activities of Heliotropium indicum L. based on database reports. For this purpose, an up-to-date literature search was carried out in the Google Scholar, Scopus, Springer Link, Web of Science, ScienceDirect, ResearchGate, PubMed, Chem Spider, Elsevier, BioMed Central, and patent offices (e.g., USPTO, CIPO, NPI, Google patents, and Espacenet) for the published materials. The findings suggest that the plant contains many important phytochemicals, including pyrrolizidine alkaloids, indicine, echinitine, supinine, heleurine, heliotrine, lasiocarpine, acetyl indicine, indicinine, indicine N-oxide, cynoglossine, europine N-oxide, heleurine N-oxide, heliotridine Noxide, heliotrine N-oxide, heliotrine, volatile oils, triterpenes, amines, and sterols. Scientific reports revealed that the herb showed antioxidant, analgesic, antimicrobial, anticancer, antituberculosis, antiplasmodial, anticataract, antifertility, wound healing, antiinflammatory, antinociceptive, antihyperglycemic, anthelmintic, diuretic, antitussive, antiglaucoma, antiallergic, and larvicidal activity. In conclusion, in vitro studies with animal models seem to show the potential beneficial effects of H. indicum against a wide variety of disorders and as a source of phytotherapeutic compounds. However, clinical studies are necessary to confirm the effects observed in animal models, determine the toxicity of the therapeutic dose and isolate the truly bioactive components. Sarkar C, Mondal M, Khanom B, Hossain MM, Hossain MS, Sureda A, et al. Heliotropium indicum L.: From Farm to a Source of Bioactive Compounds with Therapeutic Activity. Evid-Based Complement Altern Med. 2021 Jun 1;2021:9965481. 10.1155/2021/9965481 1741-4288 1741-427X Evidence-Based Complementary and Alternative Medicine https://hdl.handle.net/20.500.13003/19620 34158818 L2013081754 2-s2.0-85108072396 https://hdl.handle.net/20.500.12105/23221 664489700001 Heliotropium indicum L.: From Farm to a Source of Bioactive Compounds with Therapeutic Activity