2026-04-29T04:08:29Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/231622024-09-22T11:14:53Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967col_20.500.12105_16972
Repisalud
author
Plaza, V
author
Giner, J
author
Curto, E
author
Alonso-Ortiz, MB
author
Orue, MI
author
Vega, JM
author
García-Cosío, Borja
author
RE-TAI Study
2024-09-18T06:42:05Z
2024-09-18T06:42:05Z
2021
Plaza V, Giner J, Curto E, Alonso-Ortiz MB, Orue MI, Vega JM, et al. Assessing Adherence by Combining the Test of Adherence to Inhalers With Pharmacy Refill Records. J Invest Allergol Clin Immunol. 2021;31(1):58-64. Epub 2019 Oct 10.
1018-9068
https://hdl.handle.net/20.500.13003/19447
https://hdl.handle.net/20.500.12105/23162
31599726
10.18176/jiaci.0461
1698-0808
Journal of Investigational Allergology and Clinical Immunology
2-s2.0-85101757066
619850400007
L2006112631
Background: The Global Initiative for Asthma (GINA) recommends the concurrent use of self-report and pharmacy refill data to assess treatment adherence. However, clinical evidence to support this combined approach is limited. Objective: To determine nonadherence to inhaler medication based on a validated questionnaire (Test of Adherence to Inhalers; TAI) and prescription refill data in a community sample of patients with chronic obstructive pulmonary disease (COPD) or asthma. Secondarily, we sought to determine the degree of concordance between these two measures. Methods: Cross-sectional, observational multicenter study in patients with asthma or COPD. Sociodemographic and clinical data were obtained from clinical records. Refill data were retrieved from electronic pharmacy databases. Participants completed the 12-item TAI during a single visit as part of routine care. Nonadherence was defined as TAI <50 or <80% pharmacy refill rate (PRR) in the previous 6 months. Results: A total of 816 patients (mean age, 60) were included. Nonadherence rates were 58.1% (TAI) and 28.6% (PRR) compared with 64.6% for the combined data (P<.0001). Concordance between the 2 measures was weak (kappa=0.205). Conclusions: These findings confirm the GINA recommendations, indicating that concomitant use of the TAI and pharmacy refill data identifies a higher percentage of nonadherent asthma or COPD patients than either instrument alone.
eng
Asthma
Adherence to therapy
COPD
Self-reported success
Patient compliance
Nebulizer
Assessing Adherence by Combining the Test of Adherence to Inhalers With Pharmacy Refill Records
research article