2026-06-14T03:32:15Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/229822024-11-28T21:18:15Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc de la Rica, Roberto author Borges Sa, Marcio author Aranda Perez, Maria author del Castillo Blanco, Alberto author Socias Mir, Antonia author Payeras Cifre, Antonio author Rialp, Gemma author Socias Crespi, Lorenzo author Masmiquel Comas, Lluis author Gonzalez-Freire, Marta author 2020-08 There is limited information available describing the clinical and epidemiological features of Spanish patients requiring hospitalization for coronavirus disease 2019 (COVID-19). In this observational study, we aimed to describe the clinical characteristics and epidemiological features of severe (non-ICU) and critically patients (ICU) with COVID-19 at triage, prior to hospitalization. Forty-eight patients (27 non-ICU and 21 ICU) with positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection were analyzed (mean age, 66 years, [range, 33-88 years]; 67% males). There were no differences in age or sex among groups. Initial symptoms included fever (100%), coughing (85%), dyspnea (76%), diarrhea (42%) and asthenia (21%). ICU patients had a higher prevalence of dyspnea compared to non-ICU patients (95% vs. 61%,p= 0.022). ICU-patients had lymphopenia as well as hypoalbuminemia. Lactate dehydrogenase (LDH), C-reactive protein (CRP), and procalcitonin were significantly higher in ICU patients compared to non-ICU (p< 0.001). Lower albumin levels were associated with poor prognosis measured as longer hospital length (r = -0.472,p< 0.001) and mortality (r = -0.424,p= 0.003). As of 28 April 2020, 10 patients (8 ICU and 2 non-ICU) have died (21% mortality), and while 100% of the non-ICU patients have been discharged, 33% of the ICU patients still remained hospitalized (5 in ICU and 2 had been transferred to ward). Critically ill patients with COVID-19 present lymphopenia, hypoalbuminemia and high levels of inflammation. De la Rica R, Borges Sa M, Aranda M, Del Castillo Blanco A, Socias Mir A, Payeras Cifre A, et al. Low Albumin Levels Are Associated with Poorer Outcomes in a Case Series of COVID-19 Patients in Spain: A Retrospective Cohort Study. Microorganisms. 2020 Aug;8(8):1106. 10.3390/microorganisms8081106 2076-2607 Microorganisms http://hdl.handle.net/20.500.13003/9909 32722020 2-s2.0-85090671889 https://hdl.handle.net/20.500.12105/22982 567059300001 COVID-19 Albumin Inflammation Low Albumin Levels Are Associated with Poorer Outcomes in a Case Series of COVID-19 Patients in Spain: A Retrospective Cohort Study