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oai:repisalud.isciii.es:20.500.12105/229812024-11-29T04:55:08Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Rodas, Lluis author Riera-Sampol, Aina author Aguilo, Antoni author Martinez, Sonia author Tauler, Pedro author 2020-08 Low-grade chronic inflammation is associated with many chronic diseases and pathological conditions. The aim of the present study was to determine the effect of regular caffeine intake, physical activity levels, and sedentary behavior on the inflammatory status in healthy participants. In total, 112 men and 132 women aged 18 to 55 years and belonging to the staff and student population of the University of the Balearic Islands volunteered to participate in this descriptive cross-sectional study. Plasma concentrations of pro-inflammatory and anti-inflammatory markers were measured. Weight, height, and body composition (bioelectrical impedance) were determined. Caffeine intake, physical activity levels and sitting time, and diet quality were determined using questionnaires. Statistical regression analysis showed that caffeine intake was a negative predictor of C-reactive protein (CRP) (p= 0.001). Body fat percentage was positively associated with CRP (p< 0.001) and inversely associated with adiponectin (p= 0.032) and interleukin (IL)-10 levels (p= 0.001). Visceral fat was the main predictor for IL-6 (p< 0.001) and tumor necrosis factor (TNF)-alpha (p< 0.001). Sitting time was found to be the main, inverse, predictor for IL-10 (p< 0.001), and a positive predictor for TNF-alpha (p< 0.001). In conclusion, regular caffeine consumption induced very limited anti-inflammatory effects. Sedentary behavior and body fat accumulation induced significant pro-inflammatory effects. Rodas L, Riera-Sampol A, Aguilo A, Martinez S, Tauler P. Effects of Habitual Caffeine Intake, Physical Activity Levels, and Sedentary Behavior on the Inflammatory Status in a Healthy Population. Nutrients. 2020 Aug;12(8):2325. http://hdl.handle.net/20.500.13003/9864 https://hdl.handle.net/20.500.12105/22981 32756464 10.3390/nu12082325 2072-6643 Nutrients 2-s2.0-85089170744 577786000001 L2004840761 Caffeine Coffee Physical activity Siting time Inflammation Body fat Effects of Habitual Caffeine Intake, Physical Activity Levels, and Sedentary Behavior on the Inflammatory Status in a Healthy Population