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00925njm 22002777a 4500 dc Sanzhez-Quesada, Cristina author Toledo, Estefanía author Gonzalez-Mata, Guadalupe author Ramos-Ballesta, Maria Isabel author Ignacio Peis, Jose author Martinez-Gonzalez, Miguel Angel author Salas-Salvado, Jordi author Corella, Dolores author Fito, Montserrat author Romaguera, Dora author Vioque, Jesus author Alonso-Gomez, Angel M author Warnberg, Julia author Martinez, J. Alfredo author Serra-Majem, Luis author Estruch, Ramon author Tinahones, Francisco J author Lapetra, Jose author Pinto, Xavier author Tur, Josep A author Garcia-Rios, Antonio author Cano-Ibanez, Naomi author Matia-Martin, Pilar author Daimiel, Lidia author Sanchez-Rodriguez, Ruben author Vidal, Josep author Vazquez, Clotilde author Ros, Emilio author Hernandez-Alonso, Pablo author Barragan, Rocio author Munoz-Martinez, Julia author López, Meritxell author Gonzalez-Palacios, Sandra author Vaquero-Luna, Jessica author Crespo-Oliva, Edelys author Zulet, M. Angeles author Diaz-Gonzalez, Vanessa author Casas, Rosa author Carlos Fernandez-Garcia, Jose author Santos-Lozano, Jose Manuel author Galera, Ana author Ripoll-Vera, Tomás author Buil-Cosiales, Pilar author Canudas, Silvia author Martinez-Lacruz, Raul author Perez-Vega, Karla-Alejandra author Ríos Olivencia, Ángel author Lloret-Macian, Rosario author Moreno-Rodriguez, Anai author Ruiz-Canela, Miguel author Babio, Nancy author Zomeño-Fajardo, María Dolores author Gaforio, José J author 2020-12 Background and aims: The aim of this study was to ascertain the association between the consumption of different categories of edible olive oils (virgin olive oils and olive oil) and olive pomace oil and ankle-brachial pressure index (ABI) in participants in the PREDIMED-Plus study, a trial of lifestyle modification for weight and cardiovascular event reduction in individuals with overweight/obesity harboring the metabolic syndrome. Methods: We performed a cross-sectional analysis of the PREDIMED-Plus trial. Consumption of any category of olive oil and olive pomace oil was assessed through a validated food-frequency questionnaire. Multivariable linear regression models were fitted to assess associations between olive oil consumption and ABI. Additionally, ABI <1 was considered as the outcome in logistic models with different categories of olive oil and olive pomace oil as exposure. Results: Among 4330 participants, the highest quintile of total olive oil consumption (sum of all categories of olive oil and olive pomace oil) was associated with higher mean values of ABI (beta coefficient: 0.014, 95% confidence interval [CI]: 0.002, 0.027) (p for trend = 0.010). Logistic models comparing the consumption of different categories of olive oils, olive pomace oil and ABI <1 values revealed an inverse association between virgin olive oils consumption and the likelihood of a low ABI (odds ratio [OR] 0.73, 95% CI [0.56, 0.97]), while consumption of olive pomace oil was positively associated with a low ABI (OR 1.22 95% CI [1.00, 1.48]). Conclusions: In a Mediterranean population at high cardiovascular risk, total olive oil consumption was associated with a higher mean ABI. These results suggest that olive oil consumption may be beneficial for peripheral artery disease prevention, but longitudinal studies are needed. Sanchez-Quesada C, Toledo E, Gonzalez-Mata G, Ramos-Ballesta MI, Ignacio Peis J, Martinez-Gonzalez MA, et al. Relationship between olive oil consumption and ankle-brachial pressure index in a population at high cardiovascular risk. Atherosclerosis. 2020 Dec;314:48-57. Epub 2020 Oct 10. 10.1016/j.atherosclerosis.2020.10.008 1879-1484 0021-9150 Atherosclerosis http://hdl.handle.net/20.500.13003/15330 33160246 L2008463055 2-s2.0-85095459060 https://hdl.handle.net/20.500.12105/22904 591758300007 Olive oil Virgin olive oils Ankle-brachial pressure index Peripheral artery disease PREDIMED-Plus trial Olive pomace oil Relationship between olive oil consumption and ankle-brachial pressure index in a population at high cardiovascular risk