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00925njm 22002777a 4500 dc Vallejo-Diez, Sara author Martin-Fernandez, Jose Maria author Sanchez-Gilabert, Almudena author Fleischer, Aarne author Gayà, Antoni author Castresana, Monica author Bachiller, Daniel author 2020-08 A 32 base pair deletion in the C-C chemokine receptor type gene (CCR5-Delta 32), the main Human Immunodeficiency Virus (HIV) co-receptor results in a non-functional protein. Individuals homozygous for the CCR5-Delta 32 mutation are resistant to HIV infection. Here we report the generation, from pro-erythroblast enriched Peripheral Blood Mononuclear Cells (PBMCs) from a naturally occurring CCR5-Delta 32/Delta 32 individual, of the fully characterized iPSC line IMEDEAi008-A. The new line has normal karyotype, carry the Delta 32 mutation in homozygosity, is free of plasmid integrations, express high levels of pluripotency markers and can differentiate into all three germ layers. Vallejo-Diez S, Martin-Fernandez JM, Sanchez-Gilabert A, Fleischer A, Gaya A, Castresana M, et al. Generation of a human iPSC line (IMEDEAi008-A) derived from natural homozygous CCR5-Delta 32 PBMCs enriched in the pro-erythroblast population [editorial]. Stem Cell Research. 2020 Aug;47:101918. Epub 2020 Jul 17. 10.1016/j.scr.2020.101918 1876-7753 1873-5061 Stem Cell Research http://hdl.handle.net/20.500.13003/17240 32702648 L2007107187 2-s2.0-85088149823 https://hdl.handle.net/20.500.12105/22895 566517800012 Generation of a human iPSC line (IMEDEAi008-A) derived from natural homozygous CCR5-Delta 32 PBMCs enriched in the pro-erythroblast population