2026-05-17T05:52:41Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/228782024-11-29T00:32:36Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967col_20.500.12105_16980col_20.500.12105_16987col_20.500.12105_16988
Repisalud
author
Perez de Llano, Luis Alejandro
author
Miravitlles, Marc
author
Golpe, Rafael
author
Alvarez-Gutierrez, Francisco Javier
author
Cisneros, Carolina
author
Almonacid, Carlos
author
Martinez-Moragon, Eva
author
Gonzalez-Barcala, Francisco-Javier
author
Ramos-Barbon, David
author
Plaza, Vicente
author
Lopez-Campos, Jose Luis
author
de-Torres, Juan Pablo
author
Casanova, Ciro
author
Garcia Rivero, Juan Luis
author
Rodriguez Hermosa, Juan
author
Calle Rubio, Myriam
author
Soler-Cataluna, Juan José
author
García-Cosío, Borja
2024-09-13T09:11:48Z
2024-09-13T09:11:48Z
2020
Perez De Llano L, Miravitlles M, Golpe R, Alvarez-Gutierrez FJ, Cisneros C, Almonacid C, et al. A Proposed Approach to Chronic Airway Disease (CAD) Using Therapeutic Goals and Treatable Traits: A Look to the Future. Int J Chronic Obstr Pulm Dis. 2020;15:2091-100.
10.2147/COPD.S263430
1178-2005
International Journal of Chronic Obstructive Pulmonary Disease
http://hdl.handle.net/20.500.13003/17134
32943862
L2005015314
2-s2.0-85091265225
https://hdl.handle.net/20.500.12105/22878
565661800001
Chronic airflow obstruction affects a wide range of airway diseases, the most frequent of which are asthma, COPD, and bronchiectasis; they are clearly identifiable in their extremes, but quite frequently overlap in some of their pathophysiological and clinical characteristics. This has generated the description of new mixed or overlapping disease phenotypes with no clear biological grounds. In this special article, a group of experts provides their perspective and proposes approaching the treatment of chronic airway disease (CAD) through the identification of a series of therapeutic goals (TG) linked to treatable traits (TT) - understood as clinical, physiological, or biological characteristics that are quantifiable using biomarkers. This therapeutic approach needs validating in a clinical trial with the strategy of identification of TG and treatment according to TT for each patient independently of their prior diagnosis.
eng
Airflow obstruction
Biomarker
Personalised medicine
COPD asthma overlap
A Proposed Approach to Chronic Airway Disease (CAD) Using Therapeutic Goals and Treatable Traits: A Look to the Future
research article