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00925njm 22002777a 4500 dc Perez de Llano, Luis Alejandro author Miravitlles, Marc author Golpe, Rafael author Alvarez-Gutierrez, Francisco Javier author Cisneros, Carolina author Almonacid, Carlos author Martinez-Moragon, Eva author Gonzalez-Barcala, Francisco-Javier author Ramos-Barbon, David author Plaza, Vicente author Lopez-Campos, Jose Luis author de-Torres, Juan Pablo author Casanova, Ciro author Garcia Rivero, Juan Luis author Rodriguez Hermosa, Juan author Calle Rubio, Myriam author Soler-Cataluna, Juan José author García-Cosío, Borja author 2020 Chronic airflow obstruction affects a wide range of airway diseases, the most frequent of which are asthma, COPD, and bronchiectasis; they are clearly identifiable in their extremes, but quite frequently overlap in some of their pathophysiological and clinical characteristics. This has generated the description of new mixed or overlapping disease phenotypes with no clear biological grounds. In this special article, a group of experts provides their perspective and proposes approaching the treatment of chronic airway disease (CAD) through the identification of a series of therapeutic goals (TG) linked to treatable traits (TT) - understood as clinical, physiological, or biological characteristics that are quantifiable using biomarkers. This therapeutic approach needs validating in a clinical trial with the strategy of identification of TG and treatment according to TT for each patient independently of their prior diagnosis. Perez De Llano L, Miravitlles M, Golpe R, Alvarez-Gutierrez FJ, Cisneros C, Almonacid C, et al. A Proposed Approach to Chronic Airway Disease (CAD) Using Therapeutic Goals and Treatable Traits: A Look to the Future. Int J Chronic Obstr Pulm Dis. 2020;15:2091-100. 10.2147/COPD.S263430 1178-2005 International Journal of Chronic Obstructive Pulmonary Disease http://hdl.handle.net/20.500.13003/17134 32943862 L2005015314 2-s2.0-85091265225 https://hdl.handle.net/20.500.12105/22878 565661800001 Airflow obstruction Biomarker Personalised medicine COPD asthma overlap A Proposed Approach to Chronic Airway Disease (CAD) Using Therapeutic Goals and Treatable Traits: A Look to the Future