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oai:repisalud.isciii.es:20.500.12105/228192024-11-28T23:12:41Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Silva, Paula author Soldevila Verdeguer, Carla author Tur, Josep A author Andreoletti, Pierre author Cherkaoui-Malki, Mustapha author Latruffe, Norbert author 2019-08-12 Mediterranean diet (MD) is the most relevant nutritional aspect of the multisecular Mediterranean civilisation which includes wine as an element of health and wellbeing when consumed with moderation. Mediterranean meals provide food micronutrients which include polyphenols, especially resveratrol from grape and red wine. MD, also called Cretan diet, has been proven to prevent diseases including cardiovascular pathologies, cancer, and to prevent aging. Interestingly, the grape and more precisely in grape skin contains the highest concentration of RSV. In consequence, red wine is the most concentrated food source of RSV found in the human diet. This review topic deals to how efficient is RSV towards alterations during the aging process; obtained from recent data of clinical trials, preclinical studies, and cell culture approach; especially RSV protecting effect on brain aging of elderly; its role on the microglial cells playing a central role in the neuro-inflammation; and in its anti-inflammatory effects on ocular diseases. Silva P, Sureda Gomila A, Tur J, Andreoletti P, Cherkaoui-Malki M, Latruffe N. How efficient is resveratrol as an antioxidant of the Mediterranean diet, towards alterations during the aging process?. Free Radic Res. 2019 Aug 12;53(Suppl 1):1101-12. Epub 2019 Oct 7. 10.1080/10715762.2019.1614176 1029-2470 1071-5762 Free Radical Research http://hdl.handle.net/20.500.13003/17438 31039629 L2003475805 2-s2.0-85074042105 https://hdl.handle.net/20.500.12105/22819 490361800001 Aging Antioxidant Mediterranean diet Resveratrol How efficient is resveratrol as an antioxidant of the Mediterranean diet, towards alterations during the aging process?