2026-06-14T10:38:21Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/227652024-11-28T14:42:44Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16961col_20.500.12105_16967col_20.500.12105_16968col_20.500.12105_16969col_20.500.12105_16982col_20.500.12105_16983col_20.500.12105_16989
Repisalud
author
Tresserra-Rimbau, Anna
author
Castro-Barquero, Sara
author
Vitelli-Storelli, Facundo
author
Becerra-Tomas, Nerea
author
Vazquez-Ruiz, Zenaida
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Diaz-Lopez, Andres
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Corella, Dolores
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Castaner, Olga
author
Romaguera, Dora
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Vioque, Jesus
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Alonso-Gomez, Angel María
author
Warnberg, Julia
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Alfredo Martinez, Jose
author
Serra-Majem, Lluis
author
Estruch, Ramon
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Tinahones, Francisco Jose
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Lapetra, Jose
author
Pinto, Xavier
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Tur, Josep A
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Lopez-Miranda, Jose
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Garcia-Molina, Laura
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Delgado-Rodriguez, Miguel
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Matia-Martin, Pilar
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Daimiel, Lidia
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Rubin-Garcia, Maria
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Vidal, Josep
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Galdon, Alba
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Ros, Emilio
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Javier Basterra-Gortari, Francisco
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Babio, Nancy
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Vicente Sorli, Jose
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Hernaez, Alvaro
author
Konieczna, Jadwiga
author
Notario-Barandiaran, Leyre
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Tojal-Sierra, Lucas
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Perez-Lopez, Jessica
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Abete, Itziar
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Alvarez-Perez, Jacqueline
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Fernandez-Garcia, Jose Carlos
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Santos-Lozano, Jose Manuel
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Galera, Ana
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Julibert, Alicia
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Ruiz-Canela, Miguel
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Martinez-Lacruz, Raul
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Perez-Vega, Karla-Alejandra
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Galmes-Panades, Aina Maria
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Pastor-Polo, Concepcion
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Moreno-Rodriguez, Anai
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Gea, Alfredo
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Fito, Montserrat
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Lamuela-Raventos, Rosa Maria
author
Salas-Salvado, Jordi
2024-09-10T13:09:44Z
2024-09-10T13:09:44Z
2019-11
Tresserra-Rimbau A, Castro-Barquero S, Vitelli-Storelli F, Becerra-Tomas N, Vazquez-Ruiz Z, Diaz-Lopez A, et al. Associations between Dietary Polyphenols and Type 2 Diabetes in a Cross-Sectional Analysis of the PREDIMED-Plus Trial: Role of Body Mass Index and Sex. Antioxidants. 2019 Nov;8(11):537.
10.3390/antiox8110537
2076-3921
Antioxidants
http://hdl.handle.net/20.500.13003/13286
31717390
2-s2.0-85076531826
https://hdl.handle.net/20.500.12105/22765
502268400033
Overweight and obesity are important risk factors for type 2 diabetes (T2D). Moving towards healthier diets, namely, diets rich in bioactive compounds, could decrease the odds of suffering T2D. However, those individuals with high body mass index (BMI) may have altered absorption or metabolism of some nutrients and dietary components, including polyphenols. Therefore, we aimed to assess whether high intakes of some classes of polyphenols are associated with T2D in a population with metabolic syndrome and how these associations depend on BMI and sex. This baseline cross-sectional analysis includes 6633 participants from the PREDIMED-Plus trial. Polyphenol intakes were calculated from food frequency questionnaires (FFQ). Cox regression models with constant time at risk and robust variance estimators were used to estimate the prevalence ratios (PRs) for polyphenol intake and T2D prevalence using the lowest quartile as the reference group. Analyses were stratified by sex and BMI groups (overweight and obese) to evaluate potential effect modification. Catechins, proanthocyanidins, hydroxybenzoic acids, and lignans were inversely associated with T2D. Hydroxycinnamic acids were directly related in men. These associations were different depending on sex and BMI, that is, women and overweight obtained stronger inverse associations.
eng
Diet
Obesity
Flavonoids
Catechins
Proanthocyanidins
Hydroxybenzoic acids
Hydroxycinnamic acids
Lignans
Phenolic acids
Associations between Dietary Polyphenols and Type 2 Diabetes in a Cross-Sectional Analysis of the PREDIMED-Plus Trial: Role of Body Mass Index and Sex
research article