2026-04-29T00:59:58Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/227192024-11-29T07:45:21Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967

00925njm 22002777a 4500 dc Baldofski, Sabrina author Mauche, Nicole author Dogan-Sander, Ezgi author Bot, Mariska author Brouwer, Ingeborg A author Paans, Nadine PG author Cabout, Mieke author Gili, Margalida author van Grootheest, Gerard author Hegerl, Ulrich author Owens, Matthew author Roca, Miquel author Visser, Marjolein author Watkins, Ed author Penninx, Brenda WJH author Kohls, Elisabeth author MooDFOOD Prevention Trial Investig author 2019-11-21 Background: There is strong evidence for a bidirectional association between depression and obesity. Several biological, psychological, and behavior-related factors may influence this complex association. Clinical impression and preliminary evidence suggest that patients with a diagnosis of major depressive disorder may endorse very different depressive symptom patterns depending on their body weight status. Until now, little is known about potential differences in depressive symptoms in relation to body weight status. Objective: The aim of this analysis is the investigation of potential differences in depressive symptom clusters (mood symptoms, somatic/vegetative symptoms, and cognitive symptoms) in relation to body weight status. Methods: Cross-sectional baseline data were derived from two large European multicenter studies: the MooDFOOD Trial and the NESDA cohort study, including persons with overweight and obesity and normal weight reporting subthreshold depressive symptoms (assessment via Inventory of Depressive Symptomatology Self-Report, IDS-SR30). Different measures for body weight status [waist-to-hip ratio (WHR) and body mass index (BMI)] were examined. Propensity score matching was performed and multiple linear regression analyses were conducted. Results: A total of n = 504 individuals (73.0% women) were analyzed. Results show that more somatic/vegetative depressive symptoms, such as pain, change in appetite and weight, gastrointestinal symptoms, and arousal-related symptoms, were significantly associated with both a higher BMI and higher WHR, respectively. In addition, being male and older age were significantly associated with higher WHR. Mood and cognitive depressive symptoms did not yield significant associations for both body weight status measures. Conclusions: Somatic/vegetative symptoms and not mood and cognitive symptoms of depression are associated with body weight status. Thus, the results support previous findings of heterogeneous depressive symptoms in relation to body weight status. In addition to BMI, other body weight status measures for obesity should be taken into account in future studies. Baldofski S, Mauche N, Dogan-Sander E, Bot M, Brouwer Ingeborg A, Paans Nadine PG, et al. Depressive Symptom Clusters in Relation to Body Weight Status: Results From Two Large European Multicenter Studies. Front Psychiatry. 2019 Nov 21;10:858. 1664-0640 http://hdl.handle.net/20.500.13003/12998 https://hdl.handle.net/20.500.12105/22719 31824355 10.3389/fpsyt.2019.00858 Frontiers in Psychiatry 2-s2.0-85076704146 501261500001 L630094882 Depression Depressive symptoms Obesity Overweight Body mass index Depressive Symptom Clusters in Relation to Body Weight Status: Results From Two Large European Multicenter Studies