2026-08-30T13:04:43Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/226992025-05-08T08:39:28Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16958col_20.500.12105_16961col_20.500.12105_16967col_20.500.12105_16978
Repisalud
author
Ramos-Martinez, Antonio
author
Calderon-Parra, Jorge
author
Miró, José María
author
Munoz, Patricia
author
Rodriguez-Abella, Hugo
author
Valerio, Maricela
author
de Alarcón, Arístides
author
Luque, Rafael
author
Ambrosioni, Juan
author
Fariñas, María Carmen
author
Goenaga, Miguel Ángel
author
Oteo, Jose Antonio
author
Martinez Marcos, Francisco Javier
author
Vinuesa, David
author
Dominguez, Fernando
author
Spanish Collaboration on Endocarditis-Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en España (GAMES)
2024-09-10T13:08:53Z
2024-09-10T13:08:53Z
2019-05-01
Ramos-Martinez Antonio, Calderon-Parra Jorge, Ma Miro Jose, Muñoz Patricia, Rodriguez-Abella Hugo, Valerio Maricela, et al. Effect of the type of surgical indication on mortality in patients with infective endocarditis who are rejected for surgical intervention. Int J Cardiol. 2019 May 01;282:24-30. Epub 2019 Jan 10.
10.1016/j.ijcard.2019.01.014
1874-1754
0167-5273
International Journal of Cardiology
http://hdl.handle.net/20.500.13003/17342
30718134
L2001522479
2-s2.0-85060892633
https://hdl.handle.net/20.500.12105/22699
460380800005
Aim: To evaluate the effect of the type of surgical indication on mortality in infective endocarditis (IE) patients who are rejected for surgery. Methods and results: From January 2008 to December 2016, 2714 patients with definite left-sided IE were attended in the participating hospitals. One thousand six hundred and fifty-three patients (60.9%) presented surgical indications. Five hundred and thirty-eight patients (32.5%) presented surgical indications but received medical treatment alone. The indications for surgery in these patients were uncontrolled infection (366 patients, 68%), heart failure (168 patients, 31.3%) and prevention of embolism (148 patients, 27.6%). One hundred and thirty patients (24.2%) presented more than one indication. The mortality during hospital admission was 60% (323 patients). The in-hospital mortality of patients whose indication for surgery was heart failure, uncontrolled infection or risk of embolism was 75.6%, 61.4% and 54.7%, respectively (p < 0.001). Surgical indications due to heart failure (OR: 3.24; CI 95%: 1.99-5.9) or uncontrolled infection (OR: 1.83; CI 95%: 1.04-3.18) were independently associated with a fatal outcome during hospital admission. Mortality during the first year was 75.4%. The mortality during the first year in patients whose indication for surgery was heart failure, uncontrolled infection or risk of embolism was 85.9%, 76.7% and 72.7%, respectively (p = 0.016). Surgical indication due to heart failure (OR: 3.03; CI 95%: 1.53-5.98) were independently associated with fatal outcome during the first year. Conclusions: The type of surgical indication is associated with mortality in IE patients who are rejected for surgical intervention. (c) 2019 Elsevier B.V. All rights reserved.
eng
Endocarditis
Mortality
Heart failure
Embolism
Bacteremia
Effect of the type of surgical indication on mortality in patients with infective endocarditis who are rejected for surgical intervention
research article