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00925njm 22002777a 4500 dc Sauleda, Jaume author Núñez, Belén author Sala, Ernest author Soriano, Joan B author 2018 Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial pneumonias. It is characterized by a chronic, progressive, fibrotic interstitial lung disease of unknown cause that occurs primarily in older adults. Its prevalence and incidence have appeared to be increasing over the last decades. Despite its unknown nature, several genetic and environmental factors have been associated with IPF. Moreover, its natural history is variable, but could change depending on the currently suggested phenotypes: rapidly progressive IPF, familial, combined pulmonary fibrosis and emphysema, pulmonary hypertension, and that associated with connective tissue diseases. Early recognition and accurate staging are likely to improve outcomes and induce a prompt initiation of antifibrotics therapy. Treatment is expected to be more effective in the early stages of the disease, while developments in treatment aim to improve the current median survival of 3?4 years after diagnosis. Sauleda J, Nunez B, Sala E, Soriano JB. Idiopathic Pulmonary Fibrosis: Epidemiology, Natural History, Phenotypes.. Med Sci (Basel). 2018;6(4). 2018 Nov 29. 10.3390/medsci6040110 2076-3271 Medical Sciences (Basel, Switzerland) http://hdl.handle.net/20.500.13003/17088 30501130 L640463172 2-s2.0-85149155256 https://hdl.handle.net/20.500.12105/22619 comorbidities evolution idiopathic pulmonary fibrosis incidence prevalence risk factors Idiopathic Pulmonary Fibrosis: Epidemiology, Natural History, Phenotypes.