2026-04-29T02:37:45Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/225882024-11-28T20:25:25Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16967
Repisalud
author
Chaplin, Alice
author
Carpene, Christian
author
Mercader, Josep
2024-09-06T09:56:00Z
2024-09-06T09:56:00Z
2018-11
Chaplin A, Carpene C, Mercader J. Resveratrol, Metabolic Syndrome, and Gut Microbiota. Nutrients. 2018 Nov;10(11):1651.
http://hdl.handle.net/20.500.13003/9044
https://hdl.handle.net/20.500.12105/22588
30400297
10.3390/nu10111651
2072-6643
Nutrients
2-s2.0-85056144665
451547700089
L624752478
Resveratrol is a polyphenol which has been shown to have beneficial effects on metabolic syndrome-related alterations in experimental animals, including glucose and lipid homeostasis improvement and a reduction in fat mass, blood pressure, low-grade inflammation, and oxidative stress. Clinical trials have been carried out to address its potential; however, results are still inconclusive. Even though resveratrol is partly metabolized by gut microbiota, the relevance of this forgotten organ had not been widely considered. However, in the past few years, data has emerged suggesting that the therapeutic potential of this compound may be due to its interaction with gut microbiota, reporting changes in bacterial composition associated with beneficial metabolic outcomes. Even though data is still scarce and for the most part observational, it is promising nevertheless, suggesting that resveratrol supplementation could be a useful tool for the treatment of metabolic syndrome and its associated conditions.
eng
Resveratrol
Gut microbiota
Metabolic syndrome
Resveratrol, Metabolic Syndrome, and Gut Microbiota
review article